Publications by authors named "Tsukamoto A"

Current-driven motion of magnetic domain walls is one of the key technologies for developing storage class memory devices. Extensive studies have revealed a variety of material systems that exhibit high-speed and/or lower power propagation of the domain walls driven by electric current. However, few studies have assessed the reliability of the operations of the memory technology.

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Three-dimensional (3D)-printed models of bones are a convenient and durable alternative to real bone specimens, and they have been used in anatomy laboratories. It is necessary to identify the precise advantages of 3D-printed models from all perspectives; not only the improvement in students' knowledge of anatomy but also the students' assessment of such models. Here, students of veterinary medicine and animal science evaluated the reproducibility and effectiveness of 3D-printed models as a learning tool by completing our questionnaires, with a focus on their understanding of the skull-morphological differences among dog breeds.

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Article Synopsis
  • Left ventricular noncompaction (LVNC) is a poorly understood genetic heart condition categorized as an unclassified cardiomyopathy, largely due to the lack of standardized diagnostic criteria and proper animal models for study.
  • This research focused on two Japanese macaques showing symptoms of LVNC and their parents, using various medical imaging and tests to analyze their heart conditions.
  • Findings indicated that both affected macaques exhibited significant myocardial abnormalities typical of LVNC, suggesting that this species may be useful for studying the disease in a laboratory setting.
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The historic Barnett effect describes how an inertial body with otherwise zero net magnetic moment acquires spontaneous magnetization when mechanically spinning. Breakthrough experiments have recently shown that an ultrashort laser pulse destroys the magnetization of an ordered ferromagnet within hundreds of femtoseconds, with the spins losing angular momentum to circularly polarized optical phonons as part of the ultrafast Einstein-de Haas effect. However, the prospect of using such high-frequency vibrations of the lattice to reciprocally switch magnetization in a nearby magnetic medium has not yet been experimentally explored.

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Introduction: In the context of collective efforts taken in Japan to control the spread of COVID-19, the state of emergency and social distancing have caused a negative impact on the mental health of all residents, including foreign communities in Japan. This study aimed to evaluate the level of anxiety and its associated factors among non-Japanese residents residing in Japan during the COVID-19 pandemic.

Methods: A web-based survey in 13 languages was conducted among non-Japanese residents living in Japan during the COVID-19 situation.

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Article Synopsis
  • A new coronavirus, SARS-CoV-2, caused the COVID-19 pandemic, with research revealing how its spike protein binds to the human hACE2 receptor, which is critical for infection.
  • Scientists utilized cell lines and a baculovirus expression vector system (BEVS) to produce the receptor binding domain (RBD) of the spike protein for further study.
  • The RBD was efficiently produced with high purity using silkworms and specific tags, yielding a protein that interacts with the hACE2 receptor; variants like Alpha, Beta, Gamma, and Delta also showed similar production and binding results.
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Single-shot optical imaging based on ultrashort lasers has revealed nonrepetitive processes in subnanosecond timescales beyond the recording range of conventional high-speed cameras. However, nanosecond photography without sacrificing short exposure time and image quality is still missing because of the gap in recordable timescales between ultrafast optical imaging and high-speed electronic cameras. Here, we demonstrate nanosecond photography and ultrawide time-range high-speed photography using a spectrum circuit that produces interval-tunable pulse trains while keeping short pulse durations.

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Postoperative ileus (POI) is a surgical complication that induces emesis and anorexia. Fuzapladib (FUZ), an inhibitor of leukocyte-function-associated antigen type 1 (LFA-1) activation, a leukocyte adhesion molecule, exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site. In this study, we examined the prophylactic impact of FUZ on POI in a mouse model.

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Diffuse idiopathic skeletal hyperostosis (DISH) is a noninflammatory spondyloarthropathy characterized by ectopic calcification of spinal cord tissue. Its etiology is possibly polygenic. However, its pathogenesis and systemic effects remain unclear.

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Based on previous studies, we synthesized a novel class of ortho- and para-naphthoquinones derivatives bearing a phenolic hydroxy or sulfonamide moiety and evaluated their in vitro antiproliferative and signal transducer and activator of transcription-3 (STAT3) phosphorylation inhibitory activities. The biological evaluations of these naphthoquinones revealed that ortho-naphthoquinones containing a phenolic hydroxyl group exhibited greater antiproliferative activity compared to compounds without a phenolic hydroxyl group. Among the synthesized para-naphthoquinones, 21, which has a condensed sulfonamide structure, showed substantially higher antiproliferative activity than that of the parent compound, and was also found to inhibit the phosphorylation of STAT3(Y705) in a dose-dependent manner.

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Study Design: Retrospective review of prospectively collected data.

Objective: This study aimed to accurately map the lower extremity muscles innervated by the lumbar spinal roots by directly stimulating the spinal roots during surgery.

Summary Of Background Data: Innervation of the spinal roots in the lower extremities has been estimated by clinical studies, anatomic studies, and animal experiments.

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Purpose: To evaluate segmental mobility with degenerative lumbar spondylolisthesis (DLS), upright lateral flexion-extension radiographs (FE) are widely used. However, some authors have described that a combination of lateral radiographs in the standing position and supine sagittal image (SS) reveal more segmental mobility than FE. The purpose of this study was to investigate the optimal method for evaluating segmental mobility with DLS.

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To propose reference values for air-kerma at the reference point (Ka,r), air-kerma area product (PKA), fluoroscopy time (FT) and number of cine images (CI) for four age groups in Japan, a nationwide questionnaire was posted to 132 pediatric catheterisation of certified facility in Japan, using the conventional post system, to which 43 facilities responded. For diagnostic cardiac angiography, reference values were as follows: Ka,r: 86, 102, 165 and 264 mGy; PKA: 9.3, 9.

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Background: Sclerosing encapsulating peritonitis (SEP) is a rare clinical syndrome characterised by fibrosis and thickening of the peritoneum with massive adhesions of the abdominal organs. In humans, abdominal tumours, such as pancreatic adenocarcinoma, can be underlying diseases of SEP. This report describes a case of SEP in a dog with pancreatic ductal adenocarcinoma.

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Aim: To evaluate the effectuality and safety of cataract surgery combined with either trabeculotomy by the microhook (µLOT) or a single iStent trabecular bypass implantation (iStent) in eyes with cataract and mild-to-moderate glaucoma.

Methods: This study enrolled subjects with mild-to-moderate open angle glaucoma with visually significant cataract who used two or more ophthalmic antiglaucoma agents between 60 and 90y of age. Patients underwent cataract surgery cooperated with either implantation of an iStent (iStent-phaco) or excisional goniotomy with the µLOT (µLOT-phaco).

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Study Design: Retrospective analysis of prospectively collected multicenter observational data.

Objective: The aim was to examine the preoperative factors affecting postoperative satisfaction following posterior lumbar interbody fusion (PLIF) and microendoscopic muscle-preserving interlaminar decompression (ME-MILD) in patients with degenerative lumbar spondylolisthesis (DLS).

Summary Of Background Data: The technique involved in DLS surgery may either be decompression alone or decompression-fixation.

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The new 2018 classification of periodontal diseases is reported to be related to tooth loss due to periodontal disease (TLPD) during supportive periodontal therapy (SPT). However, few reports have evaluated this relationship for Asians or have analyzed the association of the new classification and TLPD by distinguishing between active periodontal therapy (APT) and SPT. In this study, we retrospectively applied the new classification to 607 Japanese periodontitis patients and examined the relationship between the new classification and annual TLPD rates per patient during the respective periods.

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Introduction: The many cases of far-out syndrome that have been reported have involved extraforaminal stenosis at L5-S1. We report two cases of extremely rare extraforaminal stenosis at L2-L3.

Case Report 1: A 59-year-old man presented with a 1/2-year history of the right leg pain.

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Abnormal DNA methylation is involved in the initiation and progression of lymphoid tumors. Hence, DNA demethylating agents are promising candidate drugs for chemotherapy against these tumors. The salicylic acid derived anti-inflammatory agent, olsalazine, reportedly suppresses DNA methyltransferase in human cells and has the potential to be clinically applied as a DNA demethylating agent.

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To propose typical values for the arrhythmia region between pulmonary vein isolation (PVI) and nonpulmonary vein isolation (non-PVI) in Japan. A nationwide questionnaire was posted to 343 facilities, to which 125 facilities (36.4%) responded.

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Objective: To meet the new standard of the annual dose limit for the eye lens recommended by the International Commission on Radiation Protection, radiation doses of neuroendovascular procedures in Japanese institutions were investigated.

Methods: Radiation doses to operators involved in 304 neuroendovascular procedures at 30 Japanese institutions were prospectively surveyed. The institutions recruited at an annual meeting of the Japanese Society for Neuroendovascular Therapy participated voluntarily.

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Ferrimagnetic rare-earth substituted metal alloys GdFeCo were shown to exhibit the phenomenon of all-optical magnetization switching via femtosecond laser pulses. All-optical magnetization switching has been comprehensively investigated in out-of-plane magnetized GdFeCo films; however, the films with the in-plane magnetic anisotropy have not yet been studied in detail. We report experimental observations of the magnetization switching of in-plane magnetized GdFeCo films by means of the femtosecond laser pulses in the presence of a small magnetic field of about 40 µT.

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We conducted a nationwide multicenter survey of various interventional radiology (IVR) procedures. Data were collected from 385 X-ray systems in 126 institutions, including 432 cine programs and 380 digital subtraction angiography (DSA) programs for diagnostic catheterization, percutaneous coronary intervention (PCI), ablation, transcatheter aortic valve implantation (TAVI), neurologic IVR, thorax IVR, abdominal IVR, and endovascular therapy (EVT). Fluoroscopic and cine dose rates were 10.

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