Significant associations of metabolic syndrome and its components with silent lacunar infarction in middle aged subjects.

Background: Metabolic syndrome (MetS) is associated with an increased risk of ischaemic stroke, including silent brain infarction. No study has examined its association with the lacunar subtype. The present cross sectional study examined the relationship between MetS, its components and silent lacunar infarction (SLI) in middle aged subjects.

Significant association between leukoaraiosis and metabolic syndrome in healthy subjects.

Objective: To investigate the relationship between leukoaraiosis (LA), which has been considered as an intermediate substitute of ischemic brain damages, and metabolic syndrome (MetS), which attracts attention as a risk factor for cerebrovascular diseases, in healthy subjects derived from various age groups.

Methods: We studied 1,030 healthy persons at ages between 28 and 78 years (mean, 52.7 years) with no history of stroke who visited a health care facility for routine health checkups.

An enzymatic assay for erythrocyte creatine as an index of the erythrocyte life time.

Objectives: To establish and estimate an enzymatic measurement of creatine in erythrocytes as an index of the erythrocyte life time.

Design And Method: The measurement of creatine in erythrocytes was performed using an enzymatic assay kit that was developed for serum and urine creatine. An erythrocyte sample was subjected to creatine measurement after hemolysis and deproteinization.