[Serum homocysteine levels in pregnant women with preeclampsia].

Preeclampsia is one of the most common and severe pregnancy complications, which ethiology remains unclear. It is certain that endothelial dysfunction plays a key role in the development of preeclampsia. Homocysteine is an important independent cardiovascular risk factor, which might induce the endothelial dysfunction observed in preeclampsia.

[Intermediate substrates in different stages of compensation of diabetes mellitus].

In this research there were studied the changes in the concentrations of pyruvate, lactic acid, maleate, beta-oxybutyric acid oxyacetyc acid, blood fats, triglycerides, cholesterol blood lipoproteins in patients in different stages of compensation of diabetes mellitus. Studied were 44 patients during ablatio retinae during latentive diabetes, 16 patients with decompensated, 12 with subcompensated, and 8 with compensated diabetes. The average age of the studied patients was 54 years.

[The level of total estrogens in the urine of cryptorchid patients].

The authors carried out studies on total estrogens in urine of healthy men as well as in men with cryptorchidism. These studies were performed on 79 men, divided into the following groups: a control group of healthy men--31; nonoperated patients--5; operated patients with cryptorchidism up to the seventh years of age--7; operated patients with cryptorchidism between 7 and 12 years of age--15; operated patient with cryptorchidism over 12 years of age--21. The hormonal analysis of total estrogens in urine were made by the modified fluorometric method of Braun.

Comparative studies on catecholamine content and glycogen phosphorylase activity in the myocardium of spontaneously hypertensive and normotensive rats.

Myocardial noradrenaline (NA) and adrenaline (A) concentrations as well as phosphorylase (PHOS) activity in spontaneously hypertensive (SHR) and normotensive Wistar (NWR) rats 1.5, 3, 6, 12 and 18 months of age were assayed. Myocardial hypertrophy as determined by the heart/body weight ratio in 1.

[Immunoenzyme methods for determining thyroid hormones].

The analytical reliability of the immunoenzyme methods for determination of the thyroid hormones thyroxin, triiodothyronine, thyroid-binding globulin, thyrotropic hormone and the thyroid-binding capacity was examined by the peroxidase activity of the marker enzyme of "Specol-11" 28 healthy controls, 28 patients with subcompensated insulin-dependent diabetes with mean duration of 8.4 years and 11 patients with hypogonadism were examined. In the diabetic patients were found changes in their thyroid state characteristic for hypothyroidism--increased thyroxin and a decrease of the thyroid-stimulating hormone with a lowered level of the binding proteins.

[Urinary excretion of free cortisol in diabetics].

The 24-h urine excretion of free cortisol was studied of 61 patients with diabetes mellitus. Its average value is significantly higher than that of healthy controls. No correlation was established between those changes and sex, age, light overweight in some of the patients, duration and type of diabetes as well as of vascular-degenerative lesions.