Effect of apo E phenotype on plasma postprandial triglyceride levels in young male adults with and without a familial history of myocardial infarction: the EARS II study. European Atherosclerosis Research Study.

The goal of the present study was to assess whether the effect of the apolipoprotein E polymorphism on postprandial lipemia explained part of the risk attributable to familial history of coronary heart disease. Cases (n = 407) were students, aged between 18 and 28 years, whose fathers had a proven myocardial infarction before the age of 55 years. Age-matched controls (n = 415) were recruited from the corresponding student registers.

High incidence of dyslipidaemia in the offspring of Greek men with premature coronary artery disease.

Aim: The present study aimed to assess the incidence and type of lipid disorders in the offspring of young Greek coronary patients.

Methods: One hundred and ninety-three children and youngsters were divided into two groups. Group A consisted of 104 children whose fathers had sustained a myocardial infarction before the age of 55 years.

Plasminogen activator inhibitor 1 is elevated in the children of men with premature myocardial infarction.

To assess whether plasminogen activator inhibitor 1 (PAI-1) activity is elevated in the progeny of young coronary men, 193 young subjects were recruited and divided into two groups. Group A consisted of 104 children whose fathers had suffered a myocardial infarction before the age of 55 ("cases"). Eighty-nine young subjects matched for age, sex, body mass index (BMI) and smoking habits without familial history of coronary artery disease (CAD) served as controls (group B).

Fibrinogen in the offspring of men with premature coronary artery disease.

We examined whether the levels of fibrinogen are elevated in the offspring of middle-aged coronary patients. One hundred and seventy-six young subjects were divided into two groups. Group A consisted of 100 children and youngsters (mean age 17 +/- 6 years) whose fathers had sustained a myocardial infarction under the age 55 years without associated history of diabetes mellitus or hypertension.

Recurrent atrial flutter in apical hypertrophic cardiomyopathy.

Palpitations are a symptom often reported by patients with apical hypertrophic cardiomyopathy (HCM), yet the arrhythmias associated with this type of HCM have not been studied adequately. Herein, a case of persistently recurrent atrial flutter in a 63-year-old Greek man with apical HCM is presented. Synchronized direct-current shocks were used twice during his hospitalization in order to convert atrial flutter to sinus rhythm.

Early detection of silent ischemia after bypass grafting.

Silent ischemia (SI) is one of the predictable factors for crises after coronary artery bypass grafting. During the last six months 31 consecutive patients (range of age fifty-one to seventy-one years) underwent twenty-four-hour electrocardiographic monitoring (Holter) in the second postoperative week under ambulatory hospital conditions (total time 750 hours). The patients were investigated by two-channel ST segment Holter (CM1CM5).

Q- versus non-Q-wave myocardial infarction: clinical characteristics and 6-month prognosis.

A prospective study of 208 consecutive survivors of acute myocardial infarction was undertaken to determine the differences between Q- and non-Q-wave infarction, concerning data from the history, clinical course, and 6-month follow-up. There were 177 patients with Q-wave infarction and 31 patients with non-Q-wave infarction. There were no significant differences for the following variables: age, sex, diabetes mellitus, smoking, positive family history, hypertension, obesity, previous infarction, history of unstable angina, heart failure or chronic obstructive pulmonary disease (COPD), Killip class in the Coronary Care Unit (CCU), arrhythmias and conduction defects in the CCU as well as drugs used.

Extent of the inferior myocardial infarction assessed by the frontal plane of the vectorcardiogram.

A correlation was made between the vectorcardiographic changes and the peak value of the L.D.H.