Trials
November 2017
Background: Effective, evidence-based interventions to prevent childhood tuberculosis (TB) in high TB/HIV-burden, resource-limited settings are urgently needed. There is limited implementation of evidence-based contact management strategies, including isoniazid preventive therapy (IPT), for child contacts of TB cases in Lesotho.
Methods/design: This mixed-methods implementation science study utilizes a two-arm cluster-randomized trial design with randomization at the health facility level.