Publications by authors named "Tschanz E"

Article Synopsis
  • The burn comb model is utilized to analyze secondary burn progression, focusing on both horizontal surface and vertical depth, which are crucial for understanding burn injuries.
  • Standardized burn injuries were inflicted on 24 male rats, with multiple assessments over time to evaluate burn depth and surrounding tissue damage.
  • Results indicated that while the superficial burns were consistent initially, significant tissue damage progressed to deeper layers within the first day, highlighting discrepancies in horizontal and vertical burn progression.
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Article Synopsis
  • Buruli ulcer (BU) is an infectious skin disease, and this study investigates its key histopathological features using 4-mm skin punch biopsies in Cameroon from 2011 to 2013.
  • The study involved 364 patients with 422 lesions, identifying that out of 99 ulcerated lesions diagnosed as BU, histological analysis confirmed BU in 32, showing specific necrotic patterns and bacterial presence.
  • The findings emphasize that punch biopsies are crucial for accurately diagnosing BU and differentiating it from other chronic ulcers, primarily characterized by subcutaneous necrosis and the detection of acid-fast bacilli.
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The authors describe the results of a program for the management of Buruli ulcers in Akonolinga (Cameroon). Its principal objective is to improve the diagnosis of dermatologic lesions and thereby to improve the indications for specific antibiotic therapy. This study, conducted in February, 2013, included 271 patients.

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Trichilemmal cyst is a benign tumor, developed from hair follicle, located mainly at the scalp. We report a clinical case of unusual location at the finger pulp confirmed by histology. The main differential diagnosis in this reported case was a whitlow.

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Background. Kaposi's sarcoma (KS) in transplant recipients is about 400 to 500 times rate in the general population. It is strongly associated to Human herpesvirus-8 (HHV-8) infection which has been found in 95% of KS lesions.

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Introduction: First aid treatment for thermal injuries with cold water removes heat and decreases inflammation. However, perfusion in the ischemic zone surrounding the coagulated core can be compromised by cold-induced vasoconstriction and favor burn progression. The aim of this study is to evaluate the effect of local warming on burn progression in the rat comb burn model.

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Syncope is caused by a wide variety of disorders. Recurrent syncope as a complication of malignancy is uncommon and may be difficult to diagnose and to treat. Primary neck carcinoma or metastases spreading in parapharyngeal and carotid spaces can involve the internal carotid artery and cause neurally mediated syncope with a clinical presentation like carotid sinus syndrome.

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Objective: To describe the cytological aspect of peritoneal washings in benign multicystic peritoneal mesothelioma (BMPM).

Methods: Three peritoneal washing specimens stained by standard cytological and histological procedures and analysed by light microscopy.

Results: The specimens showed an abundance of monomorphous mesothelial cells devoid of atypia or mitoses.

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Results of studies conducted in the last 2 decades suggest that the detection of high-grade dysplasia in patients with Barrett esophagus is the harbinger of a synchronous adenocarcinoma, which remains undetected even by rigorous biopsy protocols but is discovered during resection of the esophagus. The reported prevalence of synchronous carcinomas ranges from 0% to 75%. Other researchers maintain that appropriate surveillance programs can be used to detect carcinomas at a curable stage and to prevent unnecessary esophagectomies.

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CD9 is a transmembrane protein that has been implicated in cell adhesion, motility and proliferation, and numerous studies have demonstrated the prognostic value of its expression in different solid tumours. The purpose of this study is to determine the predictive value of CD9 in squamous cell carcinoma (SCC) of the head and neck. A total of 153 cases were examined for CD9 expression using immunohistochemistry applied on formalin-fixed, paraffin-embedded tissue.

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