Publications by authors named "Tsai-Wei Chou"
Definitive concurrent chemoradiation (CCRT) is the standard treatment for cervical esophageal cancer and non-surgical candidates. Initial treatment response affects survival; however, few validated markers are available for prediction. This study evaluated the clinical variables and chemoradiation parameters associated with treatment response.
View Article and Find Full Text PDFArticle Synopsis
- * Key findings indicated that factors like poor performance status, high heart radiation exposure (V10), and elevated neutrophil-to-lymphocyte ratio (NLR) at baseline and follow-up were linked to shorter overall survival (OS) times.
- * The median OS for patients was 13 months, and specific thresholds for performance status, heart V10, and NLR were established as significant predictors of survival.
Background: The prognostic significance of radiation dose to the lung or heart is unknown in esophageal cancer patients receiving neoadjuvant chemoradiotherapy followed by surgery (trimodal therapy). This study aimed to determine the association between lung and heart radiation dose volumes and prognosis of esophageal cancer after trimodal therapy.
Methods: This study reviewed 123 esophageal cancer patients treated with trimodal therapy in two tertiary institutions between 2010 and 2015.