Polyethyleneimine/fucoidan polyplexes as vaccine carriers for enhanced antigen loading and dendritic cell activation.

Vaccination is one of the most effective strategies for preventing infectious diseases. Recently, most research has centered on the development of protein subunit vaccines due to their safety. However, their low immunogenicity remains a challenge.

dbPTM in 2019: exploring disease association and cross-talk of post-translational modifications.

The dbPTM (http://dbPTM.mbc.nctu.

dbAMP: an integrated resource for exploring antimicrobial peptides with functional activities and physicochemical properties on transcriptome and proteome data.

Antimicrobial peptides (AMPs), naturally encoded from genes and generally contained 10-100 amino acids, are crucial components of the innate immune system and can protect the host from various pathogenic bacteria, as well as viruses. In recent years, the widespread use of antibiotics has inspired the rapid growth of antibiotic-resistant microorganisms that usually induce critical infection and pathogenesis. An increasing interest therefore was motivated to explore natural AMPs that enable the development of new antibiotics.