Publications by authors named "Tsadkan Gebremeskel Haile"

Being biocompatible, less toxic, cheap, easily available, and environmentally friendly, there is an increased trust in natural polymers in the drug delivery system. Mucilages, among the natural polymers, are the primary metabolites of plants that have been widely utilized in pharmaceutical manufacturing for different purposes, and mucoadhesive is one among them. The present study was designed to investigate the use of LSM as a mucoadhesive polymer using ibuprofen as a model drug.

View Article and Find Full Text PDF

Various species of the genus have been investigated for different pharmaceutical applications as excipients, yet a study on the potential use of mucilage (GFM) as a suspending agent is lacking. Thus, this study is aimed at evaluating the efficacy of mucilage (GFM) as a suspending agent in metronidazole benzoate suspension. The suspensions were prepared using 0.

View Article and Find Full Text PDF

Gum and mucilages from natural sources are in recent times increasingly investigated for pharmaceutical applications. Different studies have shown that the gum and mucilage fraction of various species of the genus were found to be effective viscosity enhancers, stabilizers, disintegrants, suspending agents, gelling agents, bioadhesives, film coating agents, and binders. However, no study has been conducted on the potential use of mucilage (GFM) as a pharmaceutical excipient.

View Article and Find Full Text PDF

Ethiopian potato is one of the tuber-bearing members of the family Lamiaceae. It is an indigenous crop in Ethiopia and important source of starch. Unprocessed native starches are structurally weak and functionally restricted for application in pharmaceutical technologies.

View Article and Find Full Text PDF