[The hygienic toxicological evaluation of the viral preparation Mamestrin].

The preparation "Mamestrine" developed in Bulgaria on the basis of NPV virus is meant for control of the Heliothis zea. Experiments are carried out on the toxic effect of the preparation, according to the requirements of FAO/WHO for assessment of the virus preparations and the acting in this country Bulgarian State Standards. On experimental animals (white rats of both sexes, white guinea pigs and white rabbits) are studied acute oral, dermal and inhalatory toxicity, subacute oral toxicity, dermal-irritation, eye-stimulation and skin-sensitizing activity, cytotoxicity and activity of the preparation in soils and waters.