Long-term neurological development of the preterm newborns.

Prematurity represents one of the risk factors of newborns' mortality, morbidity and derangements of long-term neurological development. With the increase of number of preterm newborns, problems with subsequent neurological development have also increased. Preterm population deserves great interest and a lot of investigations have been carried out in order to study their development dynamically.

[Assessment of psychomotor development in preschool and early preschool children, as a long term outcome of neonatal bacterial meningitis].

Disorder of the cognitive function and psychomotor retardation in the preschool and early preschool children is a result of neonatal bacterial meningitis in most cases. We have investigated 142 patients after neonatal bacterial meningitis and bacterial sepsis. We followed these children during 7 years (1998-2005).

[Predictive value of neurological evaluation of newborns].

The correct management of perinatal period, timely recognition and intervention of existing and prospective problems, definition of preventive measures gives us an opportunity to avoid and reduce all possible pathologic conditions, complications and their consequences. The goal of our investigation was the evaluation of neurological assessment of the pre-term and full-term newborn infants using Dubowitz scale and establishment of relations between obtained indices and neurodevelopmental outcome in children of this cohort. It was shown that Dubowitz neurological scale for infants gives an opportunity not only to separate the norm from pathology and detect particular problems of neonatal period, but also to determine contiguous conditions and define risk-factors.

[Early predictors of neurodevelopmental outcome of neonatal bacterial meningitis].

154 patients, who were hospitalized in M. Iashvili Children's central hospital in 1998-2005 were investigated. In 70 cases the diagnosis was neonatal bacterial meningitis, in 62 cases -- bacterial sepsis and neonatal meningitis and 22 cases patients were in control group with the diagnosis of neonatal bacterial sepsis.