[Proliferative activity of the matrix cells in lateral ventricles and granule cells in the dentate gyrus of the hippocampus in rats after pre- and postnatal alcoholic intoxication].

The treatment of pregnant and lactating female rats with ethanol inhibits the proliferation of matrix cells in the lateral brain ventricles of fetuses and, during the early postnatal period, of granule cells in the dentate gyrus and cells of the ventral horn of Ammon. A low proliferation rate leads to a decrease in the number of neurons forming the granule layer of the dentate gyrus and pyramidal neurons in the CA-1 field of the horn of Ammon.

[The differentiation of locus coeruleus neurons after their allotransplantation into the preliminarily denervated hippocampus of white rats].

The suspension of embryonic locus coeruleus (LC) was transplanted into outbred albino rat hippocampus after its preliminary 6-hydroxy-dopamine-induced denervation. Immunohistochemical and morphometric analysis revealed that 3 months after the transplantation, embryonic noradrenergic LC cells which have completed their histogenesis in recipient hippocampus, appear as differentiated multipolar and fusiform cells, typical to LC. Intrahippocampal allotransplants of rat embryonic LC were also demonstrated to normalize the level of orientation activity in an open area, that was significantly reduced after administration of 6-hydroxy-dopamine to the animals.

[Morpho-functional characteristics of septum pellucidum cells in a tissue culture in newborn rats].

In the conditions of cultivation of the transparent septum cells of newborn rat all cell types, inherent in this structure in vivo, are preserved and differentiate. The bioelectric activity is expressed in generating continuous pulse activity from the 9th day of cultivation on, thus suggesting the organotypic culture maturation.

[Morphofunctional characteristics of spinal cord neurons in the early stages of cultivation].

A study of the ultrastructural peculiarities of the spinal cord neural cells in 14 day old chick embryos at the early stages of cultivation has shown that adaptation processes are completed within the first days of explant cultivation. Further cultivation leads to the differentiation of neurons and to the recovery of their capacity of bioelectrical activity.