[The role of vitamin E in the body].

The basic experimental data obtained at the Department of Coenzymes' Biochemistry of the A. V. Palladin Institute of Biochemistry of the Ukr.

[The biochemical role of selenium in animal orgamisms].

Data on the biochemical function of selenium in animal and human organism are generalized from the view point of its participation in the active centre of glutathione peroxidase and its general anabolic effect. Now it is assumed that many chronical human diseases such as cancer, cardiovascular insufficiency, atherosclerosis, pancreas insufficiency and other may be connected with selenium deficiency in human nutrition. A problem is considered on ecological and endogenous factors controlling the availability of selenium in animals.

[Glutathione peroxidase and glutathione reductase activity in the rat liver after the administration of sodium selenite].

Sodium selenite 24h after its single administration to rats causes an increase in the activity of glutathione peroxidase and glutathione reductase in the liver tissue. 6 h after the selenium administration the enzymes activity does not differ from the control. Doses of 0.

[Glutathione peroxidase and glutathione reductase activity in rat liver following administration of vitamin E and methionine].

A single introduction of vitamin E and D,L-methionine to rats kept on the vivarium ration or their addition to protein-free diet separately does not affect the glutathionperoxidase and glutathionreductase activities in the liver. A simultaneus introdyction of the vitamin and methionine causes an increase in the glutathionperoxidase activity, without changing the glutathionreductase activity. Vitamin E prevents from increasing the glutathionperoxidase and glutathionreductase activities due to selenium.