Publications by authors named "Trygve Sundby Hall"

Article Synopsis
  • The study assessed the relationship between frailty, illness severity, and survival rates after hospital discharge in older adults admitted with acute illnesses.
  • Using data from 195 participants (average age 86), researchers measured frailty using the Clinical Frailty Scale and illness severity with the New Early Warning Score 2 and a laboratory index, tracking survival for 20 months post-discharge.
  • Findings indicated that higher frailty and illness severity scores were linked to decreased post-discharge survival, with frailty having a greater impact on survival in patients with more severe illnesses.
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Objectives: In the MITOCARE study, reperfusion injury was not prevented after administration of the mitochondrial permeability transition pore (mPTP) opening inhibitor, TRO40303, in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). The effects of TRO40303 on pro-inflammatory cytokines and acute-phase proteins were assessed.

Methods: STEMI patients (n = 163, mean age 62 years) with chest pain within 6 h before admission for pPCI were randomized to intravenous bolus of TRO40303 (n = 83) or placebo (n = 80) prior to reperfusion.

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