Publications by authors named "Trupti Nagendra Prasad"
Article Synopsis
- Bone fragility is a growing concern for people with diabetes, who face a higher fracture risk than those without the condition.
- The mechanisms behind this fragility are complicated and involve issues related to blood vessels, inflammation, and mechanical changes in bones.
- While DEXA scans show low bone mineral density (BMD) in type 1 diabetes, type 2 diabetes patients may have normal or increased BMD yet still face a high fracture risk, suggesting DEXA may underestimate this danger.
Introduction: This article concisely overviews the complex relationship between obesity and bone health. Obesity, characterized by excessive fat accumulation, has been traditionally associated with higher bone mineral density. Also, recent data suggest a favorable bone microarchitecture profile in these patients.
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- * Eligible participants are postmenopausal women aged 50 and older, with a history of T2D and certain bone health indicators; those with specific prior conditions or treatments are excluded.
- * Participants will be randomly assigned to receive one of three treatments (zoledronate, denosumab, or teriparatide) or just standard care, and the study will assess changes in bone mineral density and fracture rates after 18 months, along with monitoring side effects.