Publications by authors named "Trupti Kad"

Article Synopsis
  • Circulating tumor cells (CTCs) are important cancer markers that help in early detection and monitoring of disease progression, but isolating and studying them is difficult due to their low numbers and variety.
  • A new cotton microfluidic substrate (CMS) has been developed which isolates CTCs efficiently from cancer patients' blood, allowing for their growth in 3D models to test drug effectiveness and resistance.
  • The CMS demonstrated superior CTC capture rates and enhanced tumor growth when using nanostructured surfaces, showing promise for future cancer diagnostic tools and treatments.
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Background: Dysbiosis in subgingival microbial communities, resulting from increased inflammatory transudate from the gingival tissues, is an important factor in initiation and development of periodontitis. Dysbiotic communities are characterized by increased numbers of bacteria that exploit the serum-like transudate for nutrients, giving rise to a proteolytic community phenotype. Here we investigate the contribution of interactions between members of a sub-gingival community to survival and development of virulence in a serum environment-modelling that in the subgingival pocket.

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2-Acetyl-1-pyrroline (2AP) has been identified as a principal aroma compound in scented rice varieties. Δ(1)-Pyrroline-5-carboxylate synthetase (P5CS) gene is reported to regulate the proline synthesis in plants and acts as the precursor of 2AP. Two scented indica rice varieties, namely Ambemohar 157 and Indrayani, were subjected to Agrobacterium tumefaciens-mediated genetic transformation containing P5CS gene.

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The flowers of Bassia latifolia are known to contain 2-acetyl-1-pyrroline (2AP), the compound responsible for pleasant aroma in basmati and other scented rice. Four growth stages of Bassia flowers were identified and 2AP contents were analysed in each stage. It was found that 2AP (3.

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