[Features of vectorcardiograms in patients with hypertension complicated by chronic heart failure with reduced left ventricle ejection fraction].

Aim: To explore the features of vectorcardiograms (VCG) of patients with essential hypertension complicated by chronic heart failure with reduced left ventricular ejection fraction (CHFrLVEF).

Materials And Methods: We analyzed VCGs of 70 hypertensive patients with CHFrLVEF and 275 hypertensive patients without clinical signs of CHF and with LVEF50%. We assessed the presence of rhythm and conduction disturbances, and the parameters of the synthesized VCG, i.

Changes in the urine volatile metabolome throughout growth of transplanted hepatocarcinoma.

Trained detection dogs distinguish between urine samples from healthy organisms and organisms with malignant tumors, suggesting that the volatile urine metabolome contains information about tumor progression. The aim of this study was to determine whether the stage of tumor growth affects the chemical differences in the urine of mice and to what extent the "olfactory image of disease" perceived by dogs coincides with the "image of disease" recorded by the mass spectrometer. We used a novel laser ionization mass spectrometry method and propose a mass spectrometric analysis without detailed interpretation of the spectrum of volatile metabolomes in urine.

[Surgical treatment of retroperitoneal neurogenic tumors in children].

Objective: To evaluate feasibility and advantages of laparoscopic access in children with retroperitoneal neurogenic tumors.

Material And Methods: A comparative analysis of postoperative results was performed in 2 groups of patients with retroperitoneal neurogenic tumors without IDRF risk factors. Different surgical approaches were applied.

Algorithm for supersonic gas jet density profile retrieval from interferometric measurement.

A novel algorithm developed for supersonic gas jet profile retrieval from interferometric measurement is presented. The algorithm uses the Fourier transform method for the phase map restoration and method based on radial profile approximation by a set of hyper-Gaussian functions and their forward Abel transform for 3D gas density profile restoration. The numerical algorithm of the 3D gas density profile restoration based on expansion of the density radial distribution by a basis of hyper-Gaussian functions is compared with algorithms of the inverse Abel transform.

Design and test of a Faraday cup for low-charge measurement of electron beams from laser wakefield acceleration.

Nowadays, laser wakefield acceleration is considered to be one of the perspective methods for GeV electron beam production. The combination of laser accelerated electrons and Compton backscattering of a probe light beam opens the possibility of creating the tabletop source of a femtosecond light beam in x-ray and gamma ranges. The project is aimed at creating a laser-driven Compton light source in ILP SB RAS in collaboration with BINP SB RAS.

Optimization of a multibeam-pumped optical parametric amplifier.

The results of numerical simulation of the output amplifier cascade of a powerful laser system based on the parametric amplification of femtosecond pulses in an LiBO crystal with multiple beams pumping are presented. The improved technique for choosing pump beam angles with minimal parasitic amplification is presented. Differences of carrier-resolving versus envelope simulations are discussed.

Coherent combining of femtosecond pulses parametrically amplified in BBO crystals.

We report on the first experimental realization of coherent combining of parametrically amplified femtosecond pulses. The proposed and implemented two-loop active stabilization system allows us to achieve 110 as relative timing jitter between combined pulses, which is necessary for efficient coherent beam combining. In each channel of the two-channel laser setup, pulses were parametrically amplified in β-BaB2O4 (BBO) crystals to 50 μJ energy, compressed to 49 fs duration, and then coherently combined with efficiency as high as 97%.

[Video-assisted surgery of Hirschsprung's disease in children].

Results of the laparoscopic treatment of 36 patients with Hirschsprung's disease were analyzed. The majority of patients were the newborns or before 12 months old. The use of laparoscopy permitted a full-fledged topical diagnostics, aganglionosis zone identification, gut mobilization and voiding.

Electrocardiographic diagnosis of left ventricular hypertrophy on the basis of dipole electrocardiotopography method.

Purpose: The aim of this study was to verify a new criterion of hypertension-related left ventricular hypertrophy (LVH) on the basis of the dipole electrocardiotopographic technique, which provides intelligible pictorial patterns and efficient quantitative parameters for recognition of pathologic states of the heart.

Methods: Standard 12-lead and vectorcardiographic measurements with the McFee-Parungao lead system were carried out for 289 echocardiographically accessed healthy subjects and hypertensive patients with LVH. The proposed parameter index of left ventricular hypertrophy for recognition of LVH is a product of the following 3 characteristics: maximum magnitude of depolarization vector, total duration of ventricular depolarization, and local spatial integral of activation duration.

New approaches to the diagnosis of left and right ventricular hypertrophy by means of dipolar electrocardiotopography.

Objective: The aim of this work was to describe a new approach to noninvasive differential diagnosis of left and right ventricular hypertrophies (LVH and RVH) caused by the arterial or lung hypertensions.

Methods: The vectorcardiographic measurements were analyzed by means of dipolar electrocardiotopography (DECARTO) technique based upon a simplified spherical model of the heart. The characteristics of LVH and RVH are obtained from the decartograms of activation duration.

[Informative value of orthogonal electrocardiogram in the diagnosis of the left ventricular hypertrophy].

Aim: To estimate the informative value of orthogonal ECG parameters for the diagnosis of left ventricular hypertrophy (LVH).

Materials And Methods: The study comprised 142 apparently healthy individuals and 125 patients with arterial hypertension (AH) and LVH (left ventricular mass index more than 125 g/m2 for males and more than 110 g/m2 for females). Characteristic curves (ROC curves) were used to describe and compare the informative value of vectorcardiographic, demapping criteria for L VH with the informavalue of the Sokolov-Lyons criterion, the Cornelian index, and the Cornelian product.

The effect of psychoemotional load on ventricular repolarization reflected in integral body surface potential maps.

The aim of the present study was to investigate the reflection of psychoemotional stress in the body surface potential distribution as documented by isointegral maps of cardiac activation and recovery. In 72 young men (18.3+/- 7.

[New approaches to diagnosis of left ventricular hypertrophy by dipolar electrocardiography].

Aim: To show possibilities of dipolar electrocardiography (DECG) in diagnosis of left ventricular hypertrophy (LVH).

Material And Methods: We made DECG in 151 healthy subjects and 158 hypertensive patients. To characterize DECG quantitatively, we used the integral activation duration index (IADI) calculated as a weighted sum of the areas with different duration of activation, module of the maximal vector QRS, QRSxIADI (IADIM).

A computer system for interpreting blood glucose data.

This paper presents an overview on the design and implementation of a computer system for the interpretation of home monitoring data of diabetic patients. The comprehensive methodology covers the major information processing steps leading from raw data to a concise summary of what has happened between two subsequent visits. It includes techniques for summarising and interpreting data, checking for inconsistency, identifying and diagnosing metabolic problems and learning from patient data.

[Videolaparoscopic nephrectomy and nephrouretherectomy in children].

The experience with 72 laparoscopic nephrectomies and nephrouretherectomies in children aged from 13 days to 14 years is reviewed. 51 children were under 3 years of age, 2 patients - under 1 month of life. Pathological changes of the kidneys with complete loss of function were indications for endoscopic surgery.

[A method for determining the heart moving electric center on surface distributed models of the cardioelectric generator].

Using mathematical models of the bioelectric generators of the heart with surface distributed configurations, it was shown that the coordinates of the moving electric center of the heart can facilitate the recognition of the global spatial position of electrogenic zones in the myocardium. These coordinates were determined by the previously proposed method from the cardioelectric potential measured noninvasively with a multichannel lead system in the framework of electrocardiographic mapping.

Changes of decartograms under gravitational acceleration and microgravity.

The Decarto technique was used to study the orthogonal ECGs recorded in 23 subjects during parabolic flights (44 records). A parameter of the instantaneous decartograms, namely the activation area (AA), which is the total area of the depolarization front projection on the image sphere, was analyzed. We compared the values of AA during the periods of horizontal flight, upward parts of all parabolas, and the initial 10 s of microgravity of all parabolas.

[Mobile cardiac electrical center: a new concept and mathematical modeling].

A method for determination of the cardiac electric center on the basis of noninvasive multichannel measurements and multipole description of the cardioelectric potential is proposed. The method provides a more accurate and stable spatial location of the cardioelectric generator as compared to other methods (in particular, those based on minimization of the quadrupole potential). The position of the electric center is a useful characteristic for topical diagnosis of the electrophysiological state and function of the heart.

[A model of spherical quasi-epicardium for mapping of the electrical potential of the heart].

Possibility of determination of the heart electric potential maps on the spherical quasiepicardium from the body surface potentials measured by means of multiple leads, is estimated. The simplified models of ventricular depolarization electric generator considered in this study, consist of sets of uniform double layers representing basic configurations of the true electric generator of the heart, while allowing an analytical calculation of the multipole components, as well as potential of the generator. The contribution of the generator multipole components to the potential on the spherical quasiepicardium is evaluated.

Assessment of electrophysiological state of heart in astronauts in terms of decartographic and conventional electrocardiographic characteristics.

Long-term observation of the heart state during specialized professional activities plays an important part in preventive medicine. This study is aimed at assessment of electrophysiological state of heart in astronauts by common electrocardiography, vectorcardiography, and dipole electrocardiotopography (DECARTO technique). The subjects observed were two astronauts performing a long-term flight at the Mir orbital station.

[Non-invasive mapping of cardiac electric potential of a specific quasi-epicardium].

A procedure was proposed for non-invasive mapping of the cardiac electrical potential or a spherical quasiepicardium from its synchronous multichannel measurement on the surface of the chest, i.e. routine electrocardiodraphic mapping.

[Effect of hemosorption on the activity of natural antioxidant enzymes in acute pancreatitis].

All forms of acute pancreatitis are followed by the development of antioxidant insufficiency of the organism which aggravates the course of the disease, makes results of treatment worse. Hemosorption facilitates activation of natural antioxidant enzymes resulting in decreased levels of underoxidated products of lipid peroxidation: in 2/3 of the patients the use of repeated sessions of hemosorption with 24-48 h intervals is indicated in order to achieve normalization of natural antioxidant defense.

[The effect of chronic internal irradiation from incorporated radionuclides on liver function].

On chronic supply to the body of a mixture of nuclear division products lanthanum-140, barium-140, tellurium-132, neodymium-147, neptunium-239, zirconium-95, niobium-95, iodine-131, cerium-141, -144, cesium-134, -137, and ruthenium-103 are detectable in liver tissue within the first months. In the 2 to 4 years following the disaster, liver tissue primarily accumulates cerium-144, radium-226, thorium-228, -232, ruthenium-106, antimony-125, and europium-154. Within the first periods the liver radionuclide content was 19 to 31% higher than that in the blood, and in the following years it was 24 to 38% higher.

[Sorption methods and laser irradiation in the treatment of suppurative and septic diseases].

The application therapy of purulent wounds with sorbents during the first phase of the wound process reduces osmotic hyperhydration of tissues around the wound, promotes normalization of pH and phagocytosis of the wound exudate, makes the healing of the wounds 32.4% quicker. The combined use of the application therapy and external laser irradiation makes the time of healing almost 2 times shorter.

[Biological value of the meat from animals implanted with betazine and diiodotyrosine and its effect on the body].

The biological value of beef and pork of the animals implanted with antithyroid preparations did not differ from that of controls in varying tests. A long-term feeding of rats with diets containing meat of young bulls and pigs, implanted with betazine and diiodotyrosine, did not influence the content of free and bound cholesterol and total phospholipids in the liver, and produced no effect on the intensity of oxidative phosphorylation in the mitochondria which was proved by the results of the morphological, histochemical and ultrastructural investigations.