Bioactivity-guided isolation of the CHCl-soluble fraction of the stems of L. (Celastraceae) was carried out to obtain a new 7',9-epoxylignan () and three 7,9':7',9-diepoxylignans (-). The absolute configuration of was elucidated based on NMR and ECD spectroscopic data interpretation.
View Article and Find Full Text PDFFrom a CHCl extract of the bark of Taxus wallichiana, six new taxoids, wallitaxanes A-F (1-6), were isolated, together with 29 known compounds. The structures of the new compounds were elucidated on the basis of spectroscopic data interpretation. Wallitaxane D (4) was identified as an opened oxetane-type taxoid having the first naturally occurring C(H)-20 acetal group, while wallitaxanes E (5) and F (6) are representative of the rare abeo-taxoid class.
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