Comparison of forces generated using compression plating versus a magnetic lengthening nail in a sawbones femur model.

Background: The purpose of this study is to compare compression generated by a Precice magnetic lengthening intramedullary nail and a 5.0 mm limited contact dynamic compression plate.

Methods: Transverse osteotomy sites were created in the femoral shaft of ten Sawbones fourth generation composite femurs.

Bupivacaine and Lidocaine Induce Apoptosis in Osteosarcoma Tumor Cells.

Background: Osteosarcoma is the most common type of bone cancer in adolescents. There have been no significant improvements in outcomes since chemotherapy was first introduced. Bupivacaine and lidocaine have been shown to be toxic to certain malignancies.

Antiproliferative effect of bupivacaine on patient-derived sarcoma cells.

Sarcomas are rare tumors with limited treatment options. Although chemotherapy is standard for certain subtypes, overall survival has not improved in several decades. Bupivacaine has been shown to induce apoptosis and prevent cell growth in multiple different types of malignancies but has not been studied in sarcoma.

Surgical Treatment of Insufficiency Fractures of the Knee.

Bone marrow lesions (BMLs) in the knee represent focal edema caused by subchondral bone attrition and microfractures to the trabecular bone. These lesions are poor prognostic indicators for several orthopaedic procedures but also have been associated with the progression of osteoarthritis. Current research is aimed at treating BMLs with the intent to improve the overall structural integrity of the subchondral bone and delay the need for arthroplasty.

Focal Periphyseal Edema: An Uncommon Cause of Adolescent Knee Pain: A Report of Three Cases.

Case: Focal periphyseal edema (FOPE) zones have only recently been described as a cause of joint pain in adolescence. The literature is limited to a few case reports and radiologic studies describing this symptomatic physeal pathology. This series describes 3 adolescent patients with magnetic resonance imaging (MRI) confirmed FOPE zones of the distal femur.

Short tau inversion recovery magnetic resonance imaging for staging and screening in myxoid liposarcoma.

Purpose: Myxoid liposarcoma has a propensity to metastasize to bone. MRI is the preferred modality for detecting bone disease. We evaluated multiple MRI sequences to determine an optimal screening method.

Use of Magnetic Growing Intramedullary Nails in Compression During Intercalary Allograft Reconstruction.

Traditionally, intercalary allograft reconstruction after tumor resection has had a high rate of complications, particularly nonunion. Plate and intramedullary nail fixation have been used alone and in combination to improve union rates. This study sought to evaluate a new technique that uses a magnetic growing intramedullary nail to compress the osteotomy sites to aid in healing and to answer 2 questions: (1) What is the union rate and the time to union when using magnetic growing intramedullary nails? (2) What complications occur with this technique? Eight patients with 15 osteotomy sites with a minimum follow-up of 14 months were retrospectively reviewed.