[Anatomic-topographic peculiarities of sub- and supratentorial petroclival meningiomas].

The data about anatomic-topographic peculiarities of petroclival sub- and supratentorial meningiomas were presented. There were operated on 24 patients, of them 5 have died. Three main topographoanatomic variants were delineated, depending on the tumor primary origin and topographic peculiarities present.

[Microsurgical anatomy of cholesteatoma of posterior cranial fossa].

Microtopographical interrelations of the posterior cranial fossa structures in the presence of cholesteatoma were studied up intraoperatively in 36 cases and while the pathomorphological investigation conduction in 6 sectional observations. Cholesteatoma mostly localizes in cerebellopontile angle and more rarely--in the IV ventricle with craniospinal spreading. It is the tumor's capsule texture what causes dense adherence of cholesteatoma with surrounding cranial nerves, vessels, incorporated frequently in her structure together with underlying cerebral substance.

[Microsurgical anatomy of a large size tumor of vestibulo-cochlear nerve].

The microsurgical anatomy peculiarities of a large size tumor of n. vestibulocochlearis (NVC) were studied, basing on intraoperative (in 380 patients) and sectional (30) observations data. The distinguishing of three main anatomic-topographical variants of a large size NVC tumor growth has great significance for elaboration of the microsurgical tumoral excision method.

[Causes of disorders of vitally significant functions in surgical treatment of extracerebral parastem tumors of the posterior cranial fossa].

The postoperative period course and an autopsy data of 68 patients operated on for n. vestibulocochlearis neurinoma, parasternal meningioma, cholesteatoma. Principal damaging factors and cerebral stem functional disorders are assigned.

[Microsurgical anatomy of meningioma of the posterior cranial fossa].

On the material of 107 intraoperative and 19 section specimens, a topographic anatomy of meningiomas of the posterior cranial fossa was studied. The groups of tumours were distinguished, depending on location of primary meningioma and direction of its growth. Tumour interrelations with the caudal cranial nerves and surrounding vessels were studied.

[Changes in the immune status of patients with brain tumors in the pre- and postoperative periods].

Changes of the immune status in patients with glioblastomas and meningiomas during the stages of surgical treatment were studied. Functional activity of lymphocytes suffers to a greater measure in patients in the preoperative period and the ratio of the lymphocyte T- and B-subpopulations changes. Preoperative management including hormonal therapy causes further inhibition of the immune status but has no effect on the degree of neurosensitization of the patients, which may be a risk factor of the development of postoperative complications of infectious-inflammatory neuroallergic etiology.

[The effect of surgical intervention on the state of the immune system in brain tumors].

In patients with benign and malignant brain tumors before the operation, the suppression of the immune system, in particular, proliferative response of lymphocytes to T- and B-mitogens was established. Preoperative preparation of the patients aggravated this process. At day 8-10 after the operation, normalization of the main indices of immunity in patients with benign tumors was noted.

[Angiographic diagnosis of cranio-orbital meningiomas].

Analysis of the results of cerebral angiography in 64 patients with cranio-orbital meningiomas provides evidence that this method of examination is of valuable diagnostic significance in determining the growth of craniobasal meningiomas into the orbit. It not only helps in determining precisely the topography of the new growth in the cavity of the skull and the orbit but aids identifying the sources of blood supply to the tumor.

[Orbital phlebography craniobasal meningiomas spreading into the orbit].

Analysis of the results of orbital phlebography performed in 39 patients with cranio-orbital meningiomas testifies to the important diagnostic value of this methods of examination in determining the spread of craniobasal meningiomas to the orbit. By means of orbital phlebography it is possible not only to precisely define the topography of the new growth in the orbital cavity, but to reveal disorders of venous drainage from the orbit and collateral tracts which provide the draining function of the superior ophthalmic vein.