Publications by authors named "Tronghieu Nguyen"

This study examines the impact of injection parameters on the weld line strength of the polyamide 6 and 30% fiberglass (PA6 + 30% FG) composite samples. The effects of filling time, packing time, packing pressure, melt temperature, and mold temperature on the ultimate tensile strength (UTS) and the elongation value of the weld line are investigated. The results reveal that the filling time factor has the lowest influence rate.

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Article Synopsis
  • * Researchers identified unique methylation markers from cell-free DNA of HCC patients and used them to train machine learning models, which successfully differentiated HCC patients from high-risk individuals without the cancer in testing.
  • * By integrating these methylation markers with existing serum biomarkers in a commercial test, they achieved improved detection accuracy for HCC, demonstrating potential for early diagnosis.
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Numerical simulations on the fin shape of a microchannel evaporator in a CO air conditioning system were performed at the inlet evaporative temperature of 10 °C and the vapor quality of 0.61. Two types of fin shapes were dealt with: the straight fins and V-fins.

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Identification of tumor-derived mutation (TDM) in liquid biopsies (LB), especially in early-stage patients, faces several challenges, including low variant-allele frequencies, interference by white blood cell (WBC)-derived mutations (WDM), benign somatic mutations and tumor heterogeneity. Here, we addressed the above-mentioned challenges in a cohort of 50 nonmetastatic colorectal cancer patients, via a workflow involving parallel sequencing of paired WBC- and tumor-gDNA. After excluding potential false positive mutations, we detected at least one TDM in LB of 56% (28/50) of patients, with the majority showing low-patient coverage, except for one TDM mapped to that recurred in 30% (15/30) of patients.

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