Publications by authors named "Trisulo Wasyanto"

Purpose: To prove that cystatin C is a predictor of major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI), either with ST-segment Elevation (AMI-EST) or without ST-segment elevation (AMI-NEST), without cardiogenic shock or renal impairment.

Patient And Methods: This was an observational cohort study. Samples were obtained from AMI patients who underwent PCI between February 2022 and March 2022 at the Intensive Cardiovascular Care Unit.

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Background: Growth Differentiation Factor-15 (GDF-15) has emerged as a biomarker that capable to predicting cardiovascular events. Recent studies suggest that GDF-15 is elevated in patients with acute myocardial infarction (AMI), but the prognostic remains incompletely defined. This study aimed to investigate the role  of GDF-15 levels with major cardiac adverse events (MACE) on three months follow up in patients with AMI.

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Article Synopsis
  • The study investigated the impact of oral N-acetylcysteine (NAC) supplementation on immune biomarkers in patients who experienced an acute myocardial infarction (AMI).
  • The trial included 32 STEMI patients divided into a NAC group and a control group, measuring levels of high-sensitivity C-reactive protein (HsCRP), myeloperoxidase (MPO), and Galectin-3 (Gal-3) before and after treatment.
  • Results showed significant decreases in HsCRP, MPO, and Gal-3 levels in the NAC group after 72 hours, indicating that NAC may have beneficial effects on immune system markers post-AMI.
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