Publications by authors named "Tristan A Loveday"
Article Synopsis
- Cholangiocarcinoma is a type of cancer affecting the bile ducts, often linked to chronic inflammation and fibrosis, and this study investigates the usefulness of the APRI score in predicting surgical outcomes for patients.
- Data from 152 patients who had surgery at the Mayo Clinic were analyzed, looking for correlations between the APRI score and various clinical factors, with a focus on survival rates.
- The results showed no significant relationship between the APRI score and demographic or tumor characteristics, indicating it is not a reliable prognostic tool for predicting post-surgical outcomes in cholangiocarcinoma patients.
Ductal carcinoma in situ (DCIS) is a risk factor for the subsequent development of invasive breast cancer. High-risk features include age <45 years, size >5 cm, high-grade, palpable mass, hormone receptor negativity, and HER2 positivity. We have previously shown that immune infiltrates are positively associated with these high-risk features, suggesting that manipulating the immune microenvironment in high-risk DCIS could potentially alter disease progression.
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