Purpose: To assess the effects of two weeks of regular phospholipid liposomal spray application on lipid layer grade, tear film stability, subjective comfort, visual acuity, and lipid deposition in silicone hydrogel contact lens wearers.
Methods: Thirty-one existing contact lens wearers were enrolled and fitted with two week planned replacement silicone hydrogel contact lenses (Acuvue Oasys) in a prospective, randomized, paired-eye, investigator-masked trial. A phospholipid liposomal spray (Tears Again) was applied to one eye (randomized) four times daily for two weeks.