Publications by authors named "Tripathi K"

This study investigates the role of Ni in CNT production using Fe-based catalysts. Among the various catalysts used, such as 40Fe-0Ni, 40Fe-1Ni, 40Fe-3Ni, 40Fe-5Ni, 40Fe-7Ni, and 40Fe-10Ni, the 40Fe-5Ni catalyst achieved a notable yield of 5.80 gC per g metal, which is higher than the 1.

View Article and Find Full Text PDF

Rheumatoid arthritis (RA), a condition characterized by joint deterioration through the action of matrix metalloproteinases (MMPs), is prevalent worldwide. Bee venom (BV) has traditionally been used in Chinese medicine for pain, arthritis, rheumatism, skin diseases, etc. BV is enriched with active substances, notably melittin and phospholipase A2 (PLA2), offering significant therapeutic potential.

View Article and Find Full Text PDF

Growing global population, escalating energy consumption, and climate change threaten future energy security. Fossil fuel combustion, primarily coal, oil, and natural gas, exacerbates the greenhouse effect driving global warming through CO emissions. To address such issues, research is focused on converting CO into valuable fuels and chemicals, which aims to reduce noxious CO and simultaneously bridge the gap between energy demands and sustainable supply.

View Article and Find Full Text PDF

Background: Older people who die from serious chronic disease typically experience long periods (months or years) of illness and complex fluctuations in their physical health and in their social, psychological and existential well-being. Our understanding of these end-of-life trajectories is very limited, focuses predominantly on physical function and clinical predictors and neglects inter-individual differences. A better understanding of end-of-life trajectories, including what is shared among people and what is individually specific, is needed for an optimal provision of palliative care and health services planning.

View Article and Find Full Text PDF

Introduction: Infertility is a significant health problem with psycho-social burden for couples. Ayurveda considers a holistic approach, including complex multimodal regimens in managing infertility. Increasing evidence has shown that Yoga as an adjuvant to infertility treatment increases pregnancy rates.

View Article and Find Full Text PDF

Triple-negative breast cancer (TNBC) has profound unmet medical need globally for its devastating clinical outcome associated with rapid metastasis and lack of targeted therapies. Recently, lipid metabolic reprogramming especially fatty acid oxidation (FAO) has emerged as a major driver of breast cancer metastasis. Analyzing the expression of major FAO regulatory genes in breast cancer, we found selective overexpression of acyl-CoA synthetase 4 (ACSL4) in TNBC, which is primarily attributed to the absence of progesterone receptor.

View Article and Find Full Text PDF

Background: Younger people are more likely to report cybercrime than older people. As older people spend more time online, this may change. If similarly exposed, risk factors including social isolation and poor health could make older adults disproportionally susceptible.

View Article and Find Full Text PDF

Herein, we introduce a mild and efficient method for synthesizing aniline biaryls and unsymmetrical phenol biaryls through iodine-catalyzed coupling of quinone imine ketals (QIKs)/quinonemonoacetals (QMAs) and -naphthols. This approach allows for the unusual formation of ortho-substituted anilines and phenols, valuable in pharmaceuticals and advanced materials but typically difficult to produce. Our method achieves high -selectivity without needing transition metals or external/internal templates.

View Article and Find Full Text PDF

Adzuki bean, an underutilized grain legume, has a significant potential for enhancing food and nutritional security. The main obstacles to developing new cultivars and promoting the adzuki bean as a mainstream pulse crop are a lack of awareness about its potential and insufficient information on crop its genetic diversity. Here, we aimed to explore the untapped potential of adzuki bean germplasm by evaluating its agro-morphological traits and diversity at the molecular level and also to identify trait-specific germplasm by utilizing 100 adzuki bean accessions conserved in the Indian National Genebank.

View Article and Find Full Text PDF

Background Objectives: A 2.5-year placebo controlled double blind trial was conducted to investigate the safety and efficacy of AYUSH- SL, a poly- herbal Ayurvedic formulation on filarial lymphedema in different endemic areas of India. Lymphatic filariasis (LF) is caused by parasitic nematodes from Wuchereria bancrofti, Brugia malayi, or B.

View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted to investigate the X-chromosome's role in Alzheimer's Disease (AD), which had been overlooked in previous genome-wide association studies.
  • The research included 115,841 AD cases and 613,671 controls, considering different X-chromosome inactivation (XCI) states in females.
  • While no strong genetic risk factors for AD were found on the X-chromosome, seven significant loci were identified, suggesting areas for future research.
View Article and Find Full Text PDF

Uncontrolled regeneration leads to neoplastic transformation. The intestinal epithelium requires precise regulation during continuous homeostatic and damage-induced tissue renewal to prevent neoplastic transformation, suggesting that pathways unlinking tumour growth from regenerative processes must exist. Here, by mining RNA-sequencing datasets from two intestinal damage models and using pharmacological, transcriptomics and genetic tools, we identified liver X receptor (LXR) pathway activation as a tissue adaptation to damage that reciprocally regulates intestinal regeneration and tumorigenesis.

View Article and Find Full Text PDF
Article Synopsis
  • * The integration of crop wild relatives (CWRs) and traditional varieties into breeding efforts can help lower the toxic ODAP content, ensuring safer consumption.
  • * Recent advancements in genomics and other omics technologies are aiding the development of grasspea varieties with reduced or absent ODAP levels, enhancing their yield and adaptability, which is crucial for coping with climate change.
View Article and Find Full Text PDF

DNA methyltransferase and poly(ADP-ribose) polymerase inhibitors (DNMTis, PARPis) induce a stimulator of interferon (IFN) genes (STING)-dependent pathogen mimicry response (PMR) in ovarian (OC) and other cancers. We now show that combining DNMTis and PARPis upregulates expression of a little-studied nucleic-acid sensor, NFX1-type zinc finger-containing 1 protein (ZNFX1). We demonstrate that ZNFX1 is a novel master regulator for PMR induction in mitochondria, serving as a gateway for STING-dependent PMR.

View Article and Find Full Text PDF

The current study explores the seasonal dynamics of microplastic (MP) pollution in the Ganga River of Varanasi City, Uttar Pradesh, India, focusing on water and sediment samples collected during pre-monsoon and post-monsoon periods. The analysis shows significant variations in MP occurrence, shape dynamics, color distribution, and size composition across diverse sampling sites. During the pre-monsoon season, MP concentrations ranged from 17 to 36 particles/L in water samples and 160 to 312 particles/kg in sediment, indicating a moderate to high level of contamination.

View Article and Find Full Text PDF

Droughts and floods are examples of extreme weather events that can result from changes in ocean temperature. Ocean temperature is a key component of the global open sea system. Currently, real-time sea surface temperature (SST) forecasts are generated by numerical models based on physics principles and influenced by boundary and initial conditions.

View Article and Find Full Text PDF
Article Synopsis
  • Fingertip amputations result in significant pain and challenges, leading to a need for effective reconstruction methods, specifically focusing on achieving both coverage and sensation.
  • This study evaluated the use of hatchet flap surgery on 35 fingers from 31 patients with distal fingertip amputations, excluding specific types not fitting criteria, over a period of 18 months.
  • Results showed that the hatchet flap provided good aesthetic results, minimal scarring, maintained tactile sensation, and allowed patients to return to daily activities within about 3 weeks, though there were a few cases of necrosis.
View Article and Find Full Text PDF

Biomass-based 3D graphene aerogels were explored as cathode materials for the fabrication of high-performance zinc-ion hybrid supercapacitors. These hybrid supercapacitors delivered a high specific capacitance of ∼353.1 F g at a current density of 0.

View Article and Find Full Text PDF

Herein, we have synthesized a three-dimensional and hydrophobic graphene incorporated carbon aerogel (G-SCA) derived from sugar. G-SCA is being used as a multifunctional sorbent material for removing various advanced water-soluble and insoluble pollutants. Initially, G-SCA is being explored for the adsorption of nitroarenes (nitrophenols, 3-nitroaniline), an insecticide (Phoskill), an antibiotic (ciprofloxacin), and a pharmaceutical drug precursor (pyridine).

View Article and Find Full Text PDF

Heparan sulfate (HS) in the vascular endothelial glycocalyx (eGC) is a critical regulator of blood vessel homeostasis. Trauma results in HS shedding from the eGC, but the impact of trauma on HS structural modifications that could influence mechanisms of vascular injury and repair has not been evaluated. Moreover, the effect of eGC HS shedding on endothelial cell (EC) homeostasis has not been fully elucidated.

View Article and Find Full Text PDF
Article Synopsis
  • Pre-harvest sprouting (PHS) is a major abiotic stress affecting mungbean, leading to reduced yield and quality, prompting a study on genetic tolerance in various genotypes.
  • A wide range of PHS tolerance was observed among 83 examined mungbean genotypes, with germplasm lines showing better resistance compared to high-yield varieties, and significant correlations were found between PHS and traits such as water imbibition capacity and germination rates.
  • Notably, smaller-seeded genotypes exhibited greater PHS tolerance, and potential genetic donors for breeding programs were identified, including genotypes M 1255, M 145, M 422, and M 1421.
View Article and Find Full Text PDF

Dyes are extensively employed in industries, namely, textiles, cosmetics, paper, pharmaceuticals, tanning, etc. The effluent released from these industries contains various kinds of harmful dyes that adversely impact living beings and the environment due to their recalcitrant and toxic nature. In this study, an effort has been made to eliminate the methylene blue (MB) from wastewater using carbon nano-onions (CNOs) produced from waste frying oil (WFO) using an economical and eco-friendly wick pyrolysis method.

View Article and Find Full Text PDF

Introduction: Data clustering is an important field of machine learning that has applicability in wide areas, like, business analysis, manufacturing, energy, healthcare, traveling, and logistics. A variety of clustering applications have already been developed. Data clustering approaches based on self-organizing map (SOM) generally use the map dimensions (of the grid) ranging from 2 × 2 to 8 × 8 (4-64 neurons [microclusters]) without any explicit reason for using the particular dimension, and therefore optimized results are not obtained.

View Article and Find Full Text PDF

Developing early maturing lentil has the potential to minimize yield losses, mainly during terminal drought. Whole-genome resequencing (WGRS) based QTL-seq identified the loci governing earliness in lentil. The genetic analysis for maturity duration provided a good fit to 3:1 segregation (F), indicating earliness as a recessive trait.

View Article and Find Full Text PDF

Fungal diseases cause substantial loss to agricultural crops, affecting both quantities and quality. Although several methods are used for preventing disease incidence, fungicides remain crucial for higher yields and better quality. But in the past, the efficacy of several fungicides has decreased due to increased cases of fungicide resistant.

View Article and Find Full Text PDF