Publications by authors named "Tricia Y J Loo"
Article Synopsis
- * The study found that the structure of tissue and how morphogens bind to receptors can slow down their diffusion, which is crucial for maintaining concentration gradients in places like the zebrafish brain.
- * Using computer simulations of brain architecture, researchers confirmed that this hindered diffusion can explain how morphogen gradients form naturally, without needing extra regulatory processes.
Eyespots on the wings of nymphalid butterflies represent colorful examples of pattern formation, yet the developmental origins and mechanisms underlying eyespot center differentiation are still poorly understood. Using CRISPR-Cas9 we re-examine the function of Distal-less (Dll) as an activator or repressor of eyespots, a topic that remains controversial. We show that the phenotypic outcome of CRISPR mutations depends upon which specific exon is targeted.
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