The cerebellum acts as the analog to the medial temporal lobe for sensorimotor memory.

The cerebellum is critical for sensorimotor learning. The specific contribution that it makes, however, remains unclear. Inspired by the classic finding that for declarative memories, medial temporal lobe (MTL) structures provide a gateway to the formation of long-term memory but are not required for short-term memory, we hypothesized that for sensorimotor memories, the cerebellum may play an analogous role.

The cerebellum acts as the analog to the medial temporal lobe for sensorimotor memory.

Unlabelled: The cerebellum is critical for sensorimotor learning. The specific contribution that it makes, however, remains unclear. Inspired by the classic finding that, for declarative memories, medial temporal lobe structures provide a gateway to the formation of long-term memory but are not required for short-term memory, we hypothesized that, for sensorimotor memories, the cerebellum may play an analogous role.

Hierarchical motor adaptations negotiate failures during force field learning.

Humans have the amazing ability to learn the dynamics of the body and environment to develop motor skills. Traditional motor studies using arm reaching paradigms have viewed this ability as the process of 'internal model adaptation'. However, the behaviors have not been fully explored in the case when reaches fail to attain the intended target.

Reliance on Haptic Assistance Reflected in Haptic Cue Weighting.

When using an automated system, user trust in the automation is an important factor influencing performance. Prior studies have analyzed trust duringsupervisory control of automation, and how trust influences reliance: the behavioral correlate of trust. Here, we investigated how reliance on haptic assistance affects performance during shared control with an automated system.

Trust in haptic assistance: weighting visual and haptic cues based on error history.

To effectively interpret and interact with the world, humans weight redundant estimates from different sensory cues to form one coherent, integrated estimate. Recent advancements in physical assistance systems, where guiding forces are computed by an intelligent agent, enable the presentation of augmented cues. It is unknown, however, if cue weighting can be extended to augmented cues.

Movement Strategy Discovery during Training via Haptic Guidance.

Haptic guidance has previously been investigated to facilitate motor skill training, whereupon a robotic device assists a trainee in executing the desired movement. However, many studies have reported a null or even detrimental effect of haptic guidance on training compared to unassisted practice. While prior studies have focused on using haptic guidance to refine a movement strategy, our study explores its effect on the discovery of a new strategy.

Grip force control during virtual object interaction: effect of force feedback,accuracy demands, and training.

When grasping and manipulating objects, people are able to efficiently modulate their grip force according to the experienced load force. Effective grip force control involves providing enough grip force to prevent the object from slipping, while avoiding excessive force to avoid damage and fatigue. During indirect object manipulation via teleoperation systems or in virtual environments, users often receive limited somatosensory feedback about objects with which they interact.

Effect of age on stiffness modulation during postural maintenance of the arm.

The ability to modify the mechanical impedance of our limbs allows us to perform a variety of motor control tasks while interacting with the environment in a stable manner. Prior work has shown that young, healthy people are capable of modulating arm stiffness via selective muscle co-contraction to account for external disturbances in various directions. Increased age detrimentally affects control of movement and stability, although the neural mechanisms underlying these deficits are not entirely understood.

Cerebellar ataxia impairs modulation of arm stiffness during postural maintenance.

Impedance control enables humans to effectively interact with their environment during postural and movement tasks, adjusting the mechanical behavior of their limbs to account for instability. Previous work has shown that people are able to selectively modulate the end-point stiffness of their arms, adjusting for varying directions of environmental disturbances. Behavioral studies also suggest that separate controllers are used for impedance modulation versus joint torque coordination.

Cerebellar motor learning: are environment dynamics more important than error size?

Cerebellar damage impairs the control of complex dynamics during reaching movements. It also impairs learning of predictable dynamic perturbations through an error-based process. Prior work suggests that there are distinct neural mechanisms involved in error-based learning that depend on the size of error experienced.

Gradual anisometric-isometric transition for human-machine interfaces.

Human-machine interfaces (HMIs) are widely used in biomedical applications, from teleoperated surgical systems to rehabilitation devices. This paper investigates a method of control that allows an HMI to transition from anisometric to isometric mode, shifting the control input from position to force as the user's movement is gradually reduced. Two different approaches for achieving this transition are discussed: one is based on the natural system dynamics, whereas the other involves selecting and controlling dynamics.

Dark-rearing-induced reduction of GABA and GAD and prevention of the effect by BDNF in the mouse retina.

Gamma-aminobutyric acid (GABA) is an important retinal neurotransmitter. We studied the expression of GABA, glutamate decarboxylase 65 (GAD65) and GAD67 by immunocytochemistry and Western blot, in the retinas of control and dark-reared C57BL/6J black mice. This study asked three questions.