Composite Hydrogel of Poly(vinyl alcohol) Loaded by Leaf Extract, Chitosan, and Sodium Alginate with In Vitro Antibacterial and Release Test.

leaves have been used traditionally as a spice, a traditional medicine for respiratory and digestive disorders, and a remedy for bacterial infections. This study reports on the synthesis of composite hydrogels using the freeze-thaw method with poly(vinyl alcohol) (PVA) as the building block loaded by leaf extract (CHLE). Additionally, chitosan (CS) and sodium alginate (SA) were also loaded, respectively, to increase the antibacterial activity and to control the extract release of the composite hydrogels.

Konjac glucomannan-based hydrogels with health-promoting effects for potential edible electronics applications: A mini-review.

Konjac glucomannan (KGM), a dietary fiber hydrocolloid polysaccharide isolated from Amorphophallus konjac tubers, has potential applications in various fields. However, the use of KGM-based hydrogels has mainly focused on the food, biomedical, and water treatment industries. KGM possesses several health benefits and could be a promising candidate for use in edible electronics.

Novel Insight into Pickering Emulsion and Colloidal Particle Network Construction of Basil Extract for Enhancing Antioxidant and UV-B-Induced Antiaging Activities.

We developed a facile preparation method of oil-in-water (O/W) Pickering emulsion in an emollient formulation using basil extract ( L.) as a solid particle stabilizer by fine-tuning the concentration and mixing steps of common cosmetic formulas, such as humectants (hexylene glycol and glycerol), surfactant (Tween 20), and moisturizer (urea). The hydrophobicity of the main phenolic compounds of basil extract (BE), namely, salvigenin, eupatorin, rosmarinic acid, and lariciresinol, supported high interfacial coverage to prevent coalescence of globules.

Physicochemical Characteristics and Antibacterial Activities of Freeze-Thawed Polyvinyl Alcohol/Andrographolide Hydrogels.

Andrographolide (AG) is one of the compounds in , which has a high antibacterial activity. This paper reports the freeze-thaw method's use to synthesize polyvinyl alcohol (PVA) hydrogels loaded with AG and its characterization. From the morphological examination, the porosity of the PVA/AG hydrogel was found to increase with the increasing AG concentration.

A freeze-thaw PVA hydrogel loaded with guava leaf extract: physical and antibacterial properties.

A polyvinyl alcohol (PVA) hydrogel loaded with guava leaf extract (GLE) has potential applications as a wound dressing with good antibacterial activity. This study succeeded in fabricating a PVA hydrogel containing GLE using the freeze-thaw (FT) method. By varying the GLE concentration, we can adjust the physical properties of the hydrogel.

ArtinM Grafted Phospholipid Nanoparticles for Enhancing Antibiotic Cellular Uptake Against Intracellular Infection.

Background And Aim: An antimicrobial delivery in the form of surface-modified lectin of lipid nanoparticles was proposed to improve cellular accumulation. ArtinM, an active toll-like receptor 2 (TLR2) agonist lectin isolated from ( seeds, was selected to induce cellular engulfment of nanoparticles within infected host cells.

Materials And Methods: Lipid nanoparticles were prepared using the emulsification technique before electrostatic adsorption of artinM.

Polyvinylpyrrolidone/cellulose acetate electrospun composite nanofibres loaded by glycerine and garlic extract with antibacterial activity and release behaviour test.

The antibacterial activity of garlic () is believed to be due to its organosulfur compounds, which can supposedly be used further in biomedical applications. This paper reported the use of electrospinning to encapsulate a garlic extract and glycerine in nanofibrous mats. Polyvinylpyrrolidone (PVP) and cellulose acetate (CA) were the building blocks of the composite fibres that served as the hydrophilic matrix to encapsulate the garlic extract with glycerine added mainly to improve the mechanical characteristics of the composite fibres.

Mangosteen peel extract ( L.) as protective agent in glucose-induced mesangial cell as model of diabetic glomerulosclerosis.

Objectives: This study aims to evaluate the activity of mangosteen peels extract (MPE) as protection agent on induced-glucose mesangial cells (SV40 MES 13 cell line ()).

Materials And Methods: MPE was performed based on maceration method. Cytotoxic assay was performed based on MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) method, while the level of TGF-β1 (Transforming growth factor-β1) and fibronectin in glucose-induced mesangial cells were assayed and determined using ELISA KIT.

Zonal release of proteins within tissue engineering scaffolds.

The manufacture of a scaffold for tissue engineering applications that can control the location and timing of growth factor release is described. The scaffold is formed by the sintering of poly(DL-lactic acid) (P(DL)LA) microparticles, plasticized with poly(ethylene glycol) (PEG), although the method can be used for many other polymer types. The microparticles were loaded with model proteins, trypsin and horseradish peroxidase (HRP), or recombinant human bone morphogenetic protein-2 (rhBMP-2).