Am J Forensic Med Pathol
September 2024
Fractures of the hyoid bone, particularly the greater horns, and thyroid cartilage (superior horns) are known to be associated with hanging deaths. Depending on the literature, the frequency of these fractures varies from 0% to 83%. The mechanism underlying these fractures is believed to be direct compression or indirect traction from the ligature.
View Article and Find Full Text PDFObjectives: To investigate the impact of adding 68Ga-DOTATATE PET/MRI to standard MRI for target volume delineation in Gamma Knife® stereotactic radiosurgery (GKSRS) for meningioma.
Methods: Seventeen patients with 18 lesions undergoing GKSRS for WHO grade 1 meningioma were enrolled in a prospective study. All patients underwent pre-treatment 68Ga-DOTATATE PET/MRI examination in addition to standard procedures.
Introduction: Gamma Knife® stereotactic radiosurgery (GKSRS) is a non-invasive alternative to surgical resection for cerebral cavernous malformations (CCMs), especially in eloquent locations.
Methodology: A retrospective review was performed on an Australian cohort of patients receiving GKSRS for CCMs at a single institution. All patients exhibited symptoms and/or radiological evidence of haemorrhage before therapy.
Circulating sex steroid concentrations vary dramatically across the year in seasonally breeding animals. The ability of circulating sex steroids to effect muscle function can be modulated by changes in intracellular expression of steroid metabolizing enzymes (e.g.
View Article and Find Full Text PDFIntroduction/purpose: This study assessed long-term clinical and radiological outcomes following treatment with combination stereotactic radiosurgery (SRS) and immunotherapy (IT) for melanoma brain metastases (BM).
Methods: A retrospective review was performed in a contemporary cohort of patients with melanoma BM at a single tertiary institution receiving Gamma Knife SRS for melanoma BM. Multivariate Cox proportional-hazards modelling was performed with a P <0.
A 15-year-old Miniature Horse mare with persistently increased plasma calcium (total and ionized) and serum parathyroid hormone concentrations was presented for suspected primary hyperparathyroidism. Ultrasonography of the thyroid region identified an enlarged heterogeneous mass axial to the right thyroid lobe suggestive of an enlarged parathyroid gland, which was further confirmed using sestamibi nuclear scintigraphy and 3-phase computed tomography. Percutaneous ultrasound-guided ethanol ablation of the mass, a method not previously described in the horse, was performed under general anesthesia resulting in rapid normalization of plasma ionized calcium and serum parathyroid hormone concentrations.
View Article and Find Full Text PDFFood consumption has been conceptualized as an integral aspect of employee well-being. Whereas most research in the organizational literature to date is motivated by individual health outcomes, we assert that eating at work also entails interpersonal implications. In this manuscript, we draw from consumption stereotype theory and suggest that workplace healthy eating affects how employees are perceived and treated at work.
View Article and Find Full Text PDFObjectives: To conduct an empirical test of a conceptual model in which sleep duration would have an indirect negative effect on cyber incivility at work, mediated by self-regulatory fatigue and moderated by agreeableness.
Design: A 2-week daily diary study in which employees completed daily surveys in the mornings and at the end of the workday.
Setting: An observational study which measured sleep and work behaviors in the daily work lives of our participants.
Objective: We sought to explore the manner in which daily challenge and hindrance stressors at work may be associated with mood the next day, through the mediating mechanisms of presleep rumination and moods experienced while asleep during dreams.
Methods: A daily diary study in which 94 adults with full-time jobs completed 2 surveys per day for 2 work weeks. Each morning, participants reported the degree to which they engaged in rumination before sleep the previous night, the affective tone of their dreams, and their mood at that moment.
Introduction: Effective recruitment and retention can be particularly difficult when research involves children from diverse backgrounds. The purpose of this article is to describe productive methods for recruiting children from diverse racial and ethnic communities. A better understanding of this process will help researchers improve recruitment efforts and better address health disparities.
View Article and Find Full Text PDFHypofractionated stereotactic radiotherapy is a treatment option for large vestibular schwannomas supported by an increasing evidence. A single institution retrospective review of large (>3.5cc) vestibular schwannomas treated with hypofractionated stereotactic radiotherapy and single-session radiosurgery was conducted.
View Article and Find Full Text PDFObjective: This study aimed to describe the imaging spectrum of developmental anomalies of the lateral portion of the cervical neural arch.
Method: This was a five-year retrospective review of consecutive computed tomography (CT) scans of the cervical spine for structural anomalies of the cervical vertebral pedicle and facets. CT, radiographs and, when available, magnetic resonance imaging studies were independently reviewed.
Background And Objective: A retrospective review of consecutive patients between January 2012 and December 2018 receiving hypofractionated stereotactic radiotherapy (HSRT) to the cavity after resection for brain metastases was performed.
Methods: Treatment was delivered using an appropriately commissioned linear accelerator. The primary outcome was time to radiological or histological confirmation of local recurrence following completion of HSRT.
Aim: Iodine-stained fragmented thromboembolism (ISFT) is a rare phenomenon encountered in the immediate aftermath of mechanical thrombectomy or rarely as a complication of post-carotid stenting. The aim was to describe the imaging appearance and discuss its pathophysiology.
Method: This is a retrospective review of patients who underwent mechanical thrombectomy for acute stroke at a single institution over the period of one year.
Forensic Sci Med Pathol
December 2019
This report details the pathological and radiological findings in a rare case of massive subcutaneous emphysema. A 74-year-old male presented with sudden onset dyspnea and facial swelling following a fall. His symptoms were refractory to treatments for anaphylaxis, which was suspected clinically, and he quickly succumbed.
View Article and Find Full Text PDFActivation of the brain renin-angiotensin system (RAS) is a pivotal step in the pathogenesis of hypertension. The paraventricular nucleus (PVN) of the hypothalamus is a critical part of the angiotensinergic sympatho-excitatory neuronal network involved in neural control of blood pressure and hypertension. However, the importance of the PVN (pro)renin receptor (PVN-PRR)-a key component of the brain RAS-in hypertension development has not been examined.
View Article and Find Full Text PDFHist Philos Life Sci
August 2017
In this paper I seek to show how cultural niche construction theory offers the potential to extend the human evolutionary story beyond the Pleistocene, through the Neolithic, towards the kind of very large-scale societies in which we live today. The study of the human past has been compartmentalised, each compartment using different analytical vocabularies, so that their accounts are written in mutually incompatible languages. In recent years social, cognitive and cultural evolutionary theories, building on a growing body of archaeological evidence, have made substantial sense of the social and cultural evolution of the genus Homo.
View Article and Find Full Text PDFBackground We report a case of hypertensive microbleeds strategically located at the attached segment (AS) and root entry zone (REZ) at the left facial nerve causing facial paralysis. Case Report A 60-year-old woman presented with sudden onset left facial paralysis. Medical history was significant for poorly controlled hypertension secondary to bilateral adrenal hyperplasia (primary hyperaldosteronism).
View Article and Find Full Text PDFSusceptibility weighted imaging (SWI) is an essential magnetic resonance imaging sequence in the assessment of acute ischemic stroke. In this article, we discuss the physics principals and clinical application of conventional SWI and multi-echo SWI sequences. We review the research evidence and practical approach of SWI in acute ischemic stroke by focusing on the detection and characterization of thromboembolism in the cerebral circulation.
View Article and Find Full Text PDFJAMA Otolaryngol Head Neck Surg
October 2016
We present a case of Listeria monocytogenes cerebral abscess with axonal spread via the subcortical U-fibres and extreme capsule on magnetic resonance imaging, with follow-up studies demonstrating serial reduction in oedema and enhancement pattern of the white-matter fibre tracts following antimicrobial treatment. We discuss the microbiological mechanism of bacterial mobility to account for these unique imaging features. Recognition of this distinct pattern of spread of L.
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