[Cytokines and their role in pathogenesis of diabetic retinopathy].

The role of cytokines is estimated in development of diabetic retinopathy. Titer of cytokines is compared in healthy subjects and patients with impaired glucose metabolism. Fundus examination and specific cytokines level assessment allowed us to conclude that cytokines directly take part in pathogenesis of retinopathy before clinical manifestation.

[Catalytic autoantibodies as a new molecular instrument in rheumatological practice].

Aim: To compare clinicopathogenetic value of DNA-hydrolizing autoantibodies or DNA-abzymes in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).

Material And Methods: We studied sera from 180 patients with SLE, 180 RA patients and 128 healthy donors matched by age and gender; assessed catalytic and cytotoxic activity of DNA-abzymes in patients with different variants of SLE and RA course.

Results: The highest catalytic and cytotoxic activities of DNA abzymes were observed in SLE patients.

[Effect of biological fluids of the body on antimicrobial activity of ethonium-modified suture material].

Ethonium in solution and on the surface of surgical threads displays different antistaphylococcal activity in the presence of biological fluids: under the influence of bile, it decreases essentially, blood serum--decreases to a less degree, urine doesn't change it. A conclusion is made that for optimal use of the ethonium and surgical threads modified with ethonium it is necessary to take into account the location of a pathological focus.

[ECG changes during the exercise test and perfusion pressure in the basin of the left coronary artery].

Variation in cumulative electrocardiographic depolarization (delta epsilon QRS) and repolarization (delta epsilon T and ST depression below 1 mm and more) parameters at threshold stress, achieved by stepwise augmentation, was compared with perfusion pressure in the left coronary arterial network, measured at coronaro-angiography, in 103 coronary patients. It is concluded that changes in cumulative ECG parameters at threshold stress can only be suggestive of a possible drop in perfusion pressure in the left coronary arterial network.