Publications by authors named "Trent Hargens"

Purpose: Physical activity (PA) guidelines suggest a link between PA, sedentary time, and sleep quality (SQ). Step cadence is an emerging proxy for PA intensity, with zero cadence (ZC) indicating sedentary time. No research has explored the relationship between ZC and SQ.

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Background: Prior work from our group suggests that caffeine increases thrombotic potential after acute exercise. The aim of this study was to determine if hemostatic responses to exercise affected by caffeine are influenced by the CYP1A2-163 C>A polymorphism.

Methods: Forty-two healthy men performed two trials in which a graded maximal exercise test was completed one hour after consuming either 6 mg/kg of caffeine or placebo.

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Background And Aims: Lipoprotein-associated Phospholipase A (Lp-PLA) is a protein produced by inflammatory cells in circulation and is associated with cardiovascular disease (CVD) risk. Physical activity (PA) is known to reduce inflammation and risk for CVD. However, Lp-PLA has yet to be examined in relation to PA and sedentary time.

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The heart rate variability threshold (HRVT) is a clinical parameter used to gain insight into autonomic balance. Prior validation of the HRVT has been with cycle ergometry, with no studies examining the viability of treadmill exercise. The purpose of this study was to examine the reliability of the HRVT during treadmill exercise, and to compare the HRVT to the ventilatory threshold (VT).

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Impedance cardiography (IC) is a non-invasive method for assessing cardiovascular hemodynamics, and has been utilised during exercise, exclusively on a cycle ergometer. Mode-specific differences in cardiovascular hemodynamics during exercise have previously been identified, but the ability of IC to identify these differences has not been explored. Therefore, we examined the repeatability of cardiovascular hemodynamics within and between exercise modes on the treadmill (TM) and cycle (CY) ergometer.

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Objective: To assess changes in physical activity (PA) after a COVID-19 shutdown on a primarily residential university campus.

Methods: Eighty students, faculty, and staff (FS) of a university (age: 32.2 ± 13.

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Article Synopsis
  • Sleep is crucial for health and academic success, but many college students report getting less sleep, which may affect their physical activity and sedentary behavior.
  • A study involving 81 college students used accelerometers to measure sleep quality, physical activity (PA), and sedentary behavior, finding that total sleep time (TST) did not correlate with PA but did relate negatively to sedentary behavior.
  • Results indicated that students with less than 6 hours of sleep per night had increased sedentary behavior and that poor sleep is more closely linked to time spent being inactive rather than time spent being active.
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Purpose: The present study was designed to evaluate the 16 weeks diabetes prevention program (DPP) combined with instructed run sprint interval training (INT) or moderate-intensity continuous training (MICT) on glycemic control, body composition, fitness, exercise adherence, and perceived exercise enjoyment in sedentary, adults with prediabetes.

Methods: Participants completed three weekly supervised sessions of INT (4-10 bouts of 30 s maximal sprints followed by a 4 min active recovery) or MICT (30-60 min at 45-55% HRR) exercise coupled with the DPP for 16 weeks. At baseline, 8 and 16 weeks, participants completed fitness and clinical assessments as well as questionnaires to assess group and time differences.

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Obstructive sleep apnea (OSA) has been linked to altered cardiovascular response to exercise. A systematic review and individual patient data (IPD) meta-analysis were conducted to assess whether OSA patients present reduced exercise capacity. PubMed, Embase and Web of Science were searched until September 2018.

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Unlabelled: Caffeine, a popular ergogenic supplement, induces neural and vascular changes that may influence coagulation and/or fibrinolysis at rest and during exercise.

Purpose: The purpose of this study was to assess the effect of a single dose of caffeine on measures of coagulation and fibrinolysis before and after a single bout of high-intensity exercise.

Methods: Forty-eight men (age, 23 ± 3 yr; body mass index, 24 ± 3 kg·m) completed two trials, with 6 mg·kg of caffeine (CAFF) or placebo (PLAC), in random order, followed by a maximal cycle ergometer test.

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Purpose: Obesity and obstructive sleep apnea (OSA) are frequent comorbid conditions. The impact of OSA on objectively measured physical activity (PA), independent of obesity, is not clear. The purpose of this study is to examine the effect of OSA on PA measured via accelerometer.

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The goal of this project was to examine the influence of a single night of sleep restriction following heavy exercise on cycling time-trial (TT) performance and skeletal muscle function in the morning. Seven recreational cyclists (age, 24 ± 7 years; peak oxygen consumption, 62 ± 4 mL·kg·min) completed 2 phases, each comprising evening (EX1) and next-morning (EX2) exercise sessions. EX1 and EX2 were separated by an assigned sleep condition: a full night of rest (CON; 7.

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Purpose: Individuals with obstructive sleep apnea (OSA) have an altered hemostatic balance; however, the exercise response is less described. The purpose of this study is to determine the hemostatic response after acute aerobic exercise in obstructive sleep apnea.

Methods: Eighteen males (nine OSA vs.

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Purpose: Current recommendations state that individuals engage in 150 min of moderate or 75 min of vigorous intensity physical activity (PA) each week. Commercial PA monitors are becoming popular for everyday use. The accuracy of these devices, however, is not well understood.

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Purpose: Obstructive sleep apnea (OSA) is a prevalent form of sleep-disordered breathing. Evidence suggests that OSA may lead to cardiac remodeling, although the literature is equivocal. Previous literature suggests a high percentage of individuals entering a cardiac rehabilitation (CR) program also have OSA.

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Background: The Framingham risk score (FRS) has long been used as a global tool to estimate coronary heart disease (CHD) risk, but data has shown that subclinical CHD may exist in those classified as low risk by FRS, and as a result, there is potential for misclassification. Lipoprotein-associated phospholipase A2 (Lp-PLA2) and carotid intima-media thickness (CIMT) are two emerging risk markers that are predictive of future CHD events.

Purpose: To examine Lp-PLA2 and CIMT values in low risk individuals, and to explore the relationship between Lp-PLA2 and CIMT.

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Background: Current research is inconclusive as to whether obstructive sleep apnea severity directly limits exercise capacity and lowers health-related quality of life (HRQoL).

Aims: The aim of this study was to evaluate the association of obstructive sleep apnea severity with determinants of exercise capacity and HRQoL.

Subjects And Methods: Subjects were evaluated by home somnography and classified as no obstructive sleep apnea (n = 43) or as having mild (n = 27), moderate or severe obstructive sleep apnea (n = 21).

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Article Synopsis
  • Decreased sleep quality and duration is linked to higher body weight and fat accumulation.
  • Sleep disorders like insomnia, obstructive sleep apnea, and restless legs syndrome raise the risk of chronic health issues, especially obesity.
  • This review will explore the connections between sleep disorders, obesity, and exercise, focusing on how they affect each other and contribute to patient outcomes.
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Purpose: Obstructive sleep apnea (OSA) increases the risk for insulin resistance (IR). The mechanisms that link the two are not clear and are frequently confounded by obesity. OSA is associated with alterations in adipose-derived hormones (adipokines) that increase IR; however, previous studies have focused on middle-aged and older adults.

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The double product is the product of the heart rate and systolic blood pressure. The double product break point (DPBP) is a physiologic threshold that occurs at similar exercise intensities to that of the ventilatory threshold (VT). The influence of aerobic exercise training on the DPBP has not yet been examined.

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Background: Obstructive sleep apnea (OSA) is characterized by a repetitive collapse of the upper airway during sleep and may affect as many as 1 in 5 adults. Although OSA appears to increase risk for metabolic syndrome in middle-aged adults, no data currently exist in a younger, preclinical cohort.

Methods: Forty-five sedentary young men: 12 overweight with OSA (OSA), 18 overweight without OSA (NOSA), and 15 normal-weight without OSA (CON).

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Purpose: The primary purpose of the study was to assess whether physical activity (PA) habits change following 4 to 6 weeks of an early outpatient cardiac rehabilitation (CR) program. A secondary purpose was to determine whether the PA habits differ on days attending CR versus not attending CR.

Methods: Fourteen men and 8 women completed the study (age = 65.

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Background: Obstructive sleep apnea (OSA) is a disorder characterized by repetitive obstructions of the upper airway. Individuals with OSA experience intermittent hypoxia, hypercapnia, and arousals during sleep, resulting in increased sympathetic activation. Chemoreflex activation, arising from the resultant oscillatory disturbances in blood gases from OSA, exerts control over ventilation, and may induce increases in sympathetic vasoconstriction, contributing to increased long-term risks for hypertension (HTN) and cardiovascular disease (CVD).

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Study Objective: To evaluate whether cardiovascular responses to maximal exercise testing and recovery are altered with obstructive sleep apnea (OSA) in overweight young adult men.

Design: Three sedentary subject groups were recruited: Overweight with OSA (OSA), overweight without OSA (No-OSA), and normal weight without OSA (Control). Presence of OSA was screened via portable diagnostic device.

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