Publications by authors named "Trent A Newman"
Heredity (Edinb)
January 2024
Article Synopsis
- The MEST gene is important for mammalian traits like placental growth and maternal care, with an imprinted isoform found in eutherian mammals but not in marsupials.
- This study compared MEST across different mammals (tammar wallaby, platypus, and mouse) to understand the evolution of its imprinting.
- Results indicate that the imprinted short isoform of MEST likely evolved in the common ancestor of mammals, but imprinting itself in eutherians happened after the split from marsupials, due to the development of a specific epigenetic region.
