Publications by authors named "Travis Ren Teen Chia"
The ISARIC 4C Mortality score was developed to predict mortality risk among patients with COVID-19. Its performance among vaccinated individuals is understudied. This is a retrospective study of all patients with SARS-CoV-2 infection admitted to the National Centre for Infectious Diseases, Singapore, from January-2020 to December-2021.
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- Community-acquired respiratory infections, particularly pneumonia, pose a significant global health challenge, and their specific causes are not well understood.
- The RESPIRO study is a prospective observational cohort study in Singapore that seeks to identify the causes of moderate-to-severe pneumonia in adults and explore factors affecting different pathogens.
- Conducted at three major hospitals, the study involves collecting clinical data and biological samples from hospitalized patients to create a detailed database and biorepository, which will improve understanding of the epidemiology and outcomes of these infections.
The Omicron-transformer: Rise of the subvariants in the age of vaccines.
Ann Acad Med Singap
November 2022
Introduction: Omicron is the latest SARS-CoV-2 variant of concern, the pathogen that causes COVID-19. Since its emergence in late 2021, Omicron has displaced other circulating variants and caused successive waves of infection worldwide throughout 2022. Omicron is characterised by the rapid emergence of many subvariants and high rates of infection in people with vaccine- and/or infection induced immunity.
View Article and Find Full Text PDFEfficiency of yeast transformation is determined by the rate of yeast endocytosis. The aim of this study was to investigate the effect of introducing amino acids and other nutrients (inositol, adenine, or p-aminobenzoic acid) in the transformation medium to develop a highly efficient yeast transformation protocol. The target of rapamycin complex 1 (TORC1) kinase signalling complex influences the rate of yeast endocytosis.
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