Publications by authors named "Travis L Thompson"
Article Synopsis
- Recent research indicates that lineage-depleted murine hematopoietic stem cells can successfully engraft and repopulate secondary recipients after being transplanted into lethally irradiated mice.
- A study was conducted to assess if different rates of radiation delivery affected the homing of these stem cells to the bone marrow and other tissues, leading to findings that nearly all irradiated groups showed a significant reduction in stem cell homing compared to unirradiated controls.
- The results challenge the idea that radiation creates necessary "space" for stem cell homing in the bone marrow, suggesting that other factors may play a role in stem cell migration and engraftment.
Objectives: To assess the effectiveness of salvage radiotherapy (RT) for a persistent or rising prostate-specific antigen (PSA) level after radical prostatectomy, and to identify the pretreatment factors that may predict for patients likely to benefit from this treatment.
Methods: Seventy-three consecutive patients were treated during a 10-year period (1989 to 1999) with RT after radical prostatectomy. Twelve patients were excluded from analysis because of either an undetectable PSA level before RT or lack of follow-up data.