Production, isolation, and shipment of clinically relevant quantities of astatine-211: A simple and efficient approach to increasing supply.

Unlabelled: The alpha emitter astatine-211 (At) is a promising candidate for cancer treatment based on Targeted Alpha (α) Therapy (TAT). A small number of facilities, distributed across the United States, are capable of accelerating α-particle beams to produce At. However, challenges remain regarding strategic methods for shipping At in a form adaptable to advanced radiochemistry reactions and other uses of the radioisotope.