Publications by authors named "Travis Francis"
It has been proposed that opiates modulate memory consolidation, but recent work has indicated that this effect may be mediated by how the drug is experienced (i.e., passive injections vs.
View Article and Find Full Text PDFConditioned stimuli (CS) paired with foot-shock can enhance memory consolidation. Because the dopamine D3 receptor (D3R) has been implicated in mediating various responses to CSs, the current study explored its potential role in modulation of memory consolidation by an avoidance CS. Male Sprague-Dawley rats trained to avoid foot-shocks in a two-way signalled active avoidance task (8 sessions, 30 trials per session, 0.
View Article and Find Full Text PDFArticle Synopsis
- The mode of administration of drugs, whether active (self-administration) or passive (yoked), can influence how these substances affect memory consolidation in rats.
- Study 1 and Study 2 investigated the effects of heroin on memory after training, using different methods of administration, and assessed changes in memory through specific tasks and conditioned responses.
- Results indicated that while heroin injections enhanced memory in certain groups, exposure to drug-related cues influenced memory similarly across all administration methods, highlighting the significance of drug administration mode on cognitive outcomes, but not on the effects of related environmental stimuli.
Background: There is evidence that post-training exposure to nicotine, cocaine, and their conditioned stimuli (CS), enhance memory consolidation in rats. The present study assessed the effects of blocking noradrenergic and dopaminergic receptors on nicotine and cocaine unconditioned and conditioned memory modulation.
Methods: Males Sprague-Dawley rats tested on the spontaneous object recognition task received post-sample exposure to 0.