Publications by authors named "Travis Boulter"
: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a neurological disorder characterized by post-exertional malaise. Despite its clinical relevance, the disease mechanisms of ME/CFS are not fully understood. The previous studies targeting brain function or metabolites have been inconclusive in understanding ME/CFS complexity.
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- A significant number of individuals with post COVID-19 condition (PCC), or long COVID, experience severe fatigue similar to chronic fatigue syndromes, and there is currently no effective medication specifically for this issue, which can be termed post-COVID fatigue syndrome (PCFS).
- Low-dose naltrexone (LDN) has been suggested as a potential off-label treatment for PCFS, but its effectiveness has only been evaluated in small studies, emphasizing the need for larger randomized trials.
- A planned phase II trial will assess LDN's impact on fatigue in individuals with PCFS in British Columbia, enrolling participants aged 19-69, and comparing LDN against a placebo over 16 weeks, with various outcomes evaluated throughout the
Introduction: Increasing evidence on long-term health outcomes following SARS CoV-2 infection shows post-viral symptoms can persist for months. These symptoms are often consistent with those of Myalgic Encephalomyelitis or Chronic Fatigue Syndrome (ME/CFS). The aim of the present study was to examine the prevalence and outcome predictors of post-viral fatigue and related symptoms 3- and 6-months following symptom onset.
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