Publications by authors named "Traversari M"
Background/objectives: Mummy studies allow to reconstruct the characteristic of a population in a specific spatiotemporal context, in terms of living conditions, pathologies and death. Radiology represents an efficient diagnostic technique able to establish the preservation state of mummified organs and to estimate the patient's pathological conditions. However, the radiological approach shows some limitations.
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- Giacomo Torno was born in Naples in 1539 or 1541 and became a member of the Clerics Regular Theatines at 18, being welcomed on October 30, 1558.
- He suffered a stroke on December 4, 1608, and experienced torment during his illness, characterized by spasms and discomfort, leading to his death 45 days later.
- Analysis of his mummified body revealed a skin discontinuity at the sacrum, suggesting a wound that occurred during his life, which has been linked to the first recorded instance of the Kennedy terminal ulcer.
Article Synopsis
- Degenerative spine disease (DSD) is becoming more common, particularly in older adults, leading to more surgeries and complications, which require thorough preoperative assessments of patient frailty.
- This study evaluated 286 patients undergoing lumbar spine fusion, using modified Frailty Indexes and assessing sarcopenia through imaging, to determine their impact on postoperative complications.
- Results showed that frailty is a strong predictor of complications post-surgery, while sarcopenia had little effect, indicating that evaluating frailty may be more critical for assessing surgical risks.
Study Design: Retrospective cohort study.
Objective: The aim of the present study was to determine if the level of training of the first assistant (resident or attending surgeon) has an influence on the radiographic outcome of AIS surgery and on the accuracy rate of the pedicle screws placement.
Summary Of Background Data: Adolescent idiopathic scoliosis (AIS) surgery is a challenging procedure that requires a dedicated team of skilled professionals.
Over the past several decades, there has been a notable increase in the total number of spinal fusion procedures worldwide. Advanced spinal fusion techniques, surgical approaches, and new alternatives in grafting materials and implants, as well as autologous cellular therapies, have been widely employed for treating spinal diseases. While the potential of cellular therapies to yield better clinical results is appealing, supportive data are needed to confirm this claim.
View Article and Find Full Text PDFAging comes with the loss of muscle and bone mass, leading to a condition known as osteosarcopenia. Circulating, cellular, and tissue biomarkers research for osteosarcopenia is relatively scarce and, currently, no established biomarkers exist. Here we find that osteosarcopenic patients exhibited elevated basophils and TNFα levels, along with decreased aPPT, PT/INR, IL15, alpha-Klotho, DHEA-S, and FGF-2 expression and distinctive bone and muscle tissue micro-architecture and biomarker expressions.
View Article and Find Full Text PDFBackground: The most effective injective treatment approach for sacroiliac joint (SIJ) pain remains unclear. Aim of this study was to quantify the safety and effectiveness of the available injective strategies to address SIJ pain.
Methods: A systematic review and meta-analysis of the literature was conducted on PubMed, Scopus, and Embase databases from inception until January 2023.
In the 1960s, Harrington instrumentation (HRI) revolutionized the surgical treatment of adolescent idiopathic scoliosis (AIS). Despite the transition to more innovative techniques, concerns regarding its impact on sagittal alignment, associations with low back pain, and correction loss have consistently persisted. The aim of this meta-analysis is precisely to evaluate the clinical and radiological outcomes, as well as the complications of patients treated with HRI over an extended follow-up period.
View Article and Find Full Text PDFAdolescent idiopathic scoliosis (AIS) is a three-dimensional structural deformity of the spine that affects 2-3% of adolescents under the age of 16. AIS etiopathogenesis is not completely understood; however, the disease phenotype is correlated to multiple genetic loci and results from genetic-environmental interactions. One of the primary, still unresolved issues is the implementation of reliable diagnostic and prognostic markers.
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- * This study reviews existing literature to identify the best timing for initiating physical therapy, using peer-reviewed articles and PRISMA guidelines, and includes 14 studies focusing on various recovery outcomes.
- * The findings show that starting physical therapy early can lead to better results in reducing low back pain and disability over time, without increasing the risk of complications, especially after procedures like lumbar discectomy.
Article Synopsis
- The study aimed to find a cutoff for predicting histological response in Ewing sarcoma based on tumor volume changes after chemotherapy.
- Out of 184 patients analyzed, a reduction of over 65% in tumor volume was identified as an optimal threshold for a good histological response, with a 45% response rate of necrosis.
- While tumor volume reduction itself did not influence survival, poor histological responses were linked to decreased relapse-free survival, indicating potential benefits from more aggressive treatments for at-risk patients.
The use of closed suction drains post posterior spinal fusion for adolescent idiopathic scoliosis (AIS) is common practice, although evidence on its impact is limited compared to that for knee and hip arthroplasty. This study aimed to assess the effect of closed suction drainage on short-term post-operative outcomes in AIS surgery. A systematic review following PRISMA guidelines was conducted, including studies comparing outcomes with and without drainage.
View Article and Find Full Text PDFPurpose: Surgical treatment of adolescent idiopathic scoliosis (AIS) requires a careful choice of fusion levels. The usual recommendation for the selection of the lowest instrumented vertebra (LIV) for double major or thoracolumbar/lumbar (TL/L) curves falls on L3 or L4. The aim of the present study is to assess if the spinal fusion with LIV selection of L3 or L4 in AIS patients has a clinical or radiological impact in terms of degenerative disc disease (DDD) in distal unfused segments at long-term follow-up.
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- The study is a systematic review and meta-analysis focusing on how correcting lumbosacral kyphosis can affect high-grade spondylolisthesis (HGS), which involves significant vertebral displacement and a kyphotic deformity.
- Results from 18 studies showed a significant decrease in pelvic tilt and an increase in sacral slope post-surgery, although changes in lumbar lordosis and thoracic kyphosis were not statistically significant.
- The findings suggest that while there are mild changes in certain spinal parameters after HGS reduction, the clinical significance of these changes is still uncertain.
Study Design: Metanalysis.
Objective: Surgical site infections (SSI) is one of the commonest postoperative adverse events after spine surgery. Frailty has been described as a valuable summary risk indicator for SSI in spine surgery.
Study Design: Retrospective cohort study.
Objectives: To assess if pedicle dysplasia is present in proximal thoracic (PT), both structural and nonstructural, compared to main thoracic (MT) curves; and to assess if it is predictive of radiographic outcomes at minimum 2 years of follow-up.
Methods: A retrospective review of surgically-treated Adolescent Idiopathic Scoliosis (AIS) patients with Lenke 1-2-3-4 curves was performed.
The purpose of the present paper is to assess if Ponte osteotomies (POs) allow for a better correction in adolescent idiopathic scoliosis (AIS) surgery and to investigate their safety profile. A systematic search of electronic databases was conducted. Inclusion criteria: comparative studies that reported the outcomes of AIS patients who underwent surgical correction through posterior-only approach with and without POs.
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- The study investigates how to manage adolescent idiopathic scoliosis by evaluating radiological indexes that predict scoliosis progression during growth phases, such as peak height velocity.
- It follows PRISMA guidelines to systematically review peer-reviewed articles that link skeletal maturity indicators to curve progression, concluding that Risser staging isn't enough for treatment decisions.
- It emphasizes the complexity of idiopathic scoliosis and the need for multiple reliable indicators to create effective management strategies, advocating for a collective scientific effort to design better algorithms for treatment.
Purpose: Brachymetatarsia is marked by the shortened length of one or more metatarsal bones. Several operative options have been suggested without demonstrating the superiority of one treatment over another. This study aims to assess the main available treatment, bone lengthening achieved, clinical outcomes, and complications pertaining to congenital brachymetatarsia interventions.
View Article and Find Full Text PDFDuring an excavation campaign in the Church of the Conversion of Saint Paul in Roccapelago (North Italy), a hidden crypt was discovered, which yielded the remains of more than 400 individuals. The crypt was used as a cemetery by the inhabitants of the village of Roccapelago between the 16th and 18th centuries. Along the north side of the crypt, an area apparently separated from the rest of the burials was found, bordered by stones, where several burials of newborns and infants were concentrated.
View Article and Find Full Text PDFBackground: Osteosarcoma is a highly aggressive malignant bone tumor that affects mainly adolescents and young adults. We analyzed serum biomarkers for their prognostic significance in children with osteosarcoma.
Methods: In this retrospective study, we investigated the prognostic factors in 210 children who were treated for appendicular osteosarcoma, including patient age and sex, tumor site and size (≥8 cm or <8 cm), presence of metastasis, chemotherapy-induced tumor necrosis, serum levels of alkaline phosphatase (AP), C-reactive protein, serum hemoglobin, lactate dehydrogenase, erythrocyte sedimentation rate (ESR), leukocyte counts, platelet count, and neutrophil-lymphocyte ratio.
The Neolithic burial of Grotta di Pietra Sant'Angelo (CS) represents a unique archaeological finding for the prehistory of Southern Italy. The unusual placement of the inhumation at a rather high altitude and far from inhabited areas, the lack of funerary equipment and the prone deposition of the body find limited similarities in coeval Italian sites. These elements have prompted wider questions on mortuary customs during the prehistory of Southern Italy.
View Article and Find Full Text PDFThe aim of the present study is to systematically review the current literature about diagnosis and treatment of acute inflammatory sacroiliitis in pregnant or post-partum women. A systematic search was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data about clinical presentation, diagnosis methods and treatment strategies were retrieved from included studies and reported in a table.
View Article and Find Full Text PDFStudy Design: This was a retrospective study.
Objective: Since a better understanding of modifiable risk factors for proximal junctional disease (PJD) may lead to improved postoperative outcomes and less need of revision surgery, the aim of the present study is to determine whether sarcopenia and osteopenia are independent risk factors for PJD in patients undergoing lumbar fusion.
Summary Of Background Data: PJD is one of the most frequent complications following posterior instrumented spinal fusion.