Publications by authors named "Trana C"

Article Synopsis
  • PVCs are common arrhythmias that can indicate underlying heart issues such as ischemia, hypertension, or inflammation, making them important for prognosis.
  • Some PVCs are linked to inherited arrhythmic syndromes, while others occur without any heart problems and are generally considered harmless.
  • Even in the absence of structural heart disease, a high burden of idiopathic PVCs, often originating from the right ventricle outflow tract, can lead to PVC-induced cardiomyopathy, which is diagnosed after ruling out other causes.
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While bradyarrhythmia is the most common arrhythmia during deglutition, tachycardias are considered to be a very rare condition with approximately 50 cases documented worldwide. The subjects are usually men with no structural heart disease or gastrointestinal pathology, and symptoms may vary from palpitations to lightheadedness or syncope. Management is based on adapting alimentary habits in combination with agents such as beta-blockers, calcium channel blockers, and class IA, IC, and III drugs.

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Article Synopsis
  • Lithium is commonly used to treat bipolar disorders but can lead to harmful ECG changes, especially during acute-on-chronic intoxication.
  • A patient with acute delirium presented with an ECG showing atrial fibrillation and other significant modifications, which were initially confused with a heart attack.
  • Accurate diagnosis of these ECG alterations is crucial for appropriate management and may necessitate changes in treatment and close monitoring.
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Cardiologists are in charge of the follow-up of patients equipped with pacemakers and defibrillators. In many situations, however, the non-specialist will have to take care of these patients. It is therefore essential that the practitioner understands the basics of how these devices work, the potential complications and the situations in which the cardiologist's intervention is necessary.

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Despite evidence supporting the effectiveness of best practices in infection prevention and management, many healthcare workers fail to implement them and evidence-based practices tend to be underused in routine practice. Prevention and management of infections across the surgical pathway should always focus on collaboration among all healthcare workers sharing knowledge of best practices. To clarify key issues in the prevention and management of infections across the surgical pathway, a multidisciplinary task force of experts convened in Ancona, Italy, on May 31, 2019, for a national meeting.

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Background: Timing and adequacy of peritoneal source control are the most important pillars in the management of patients with acute peritonitis. Therefore, early prognostic evaluation of acute peritonitis is paramount to assess the severity and establish a prompt and appropriate treatment. The objectives of this study were to identify clinical and laboratory predictors for in-hospital mortality in patients with acute peritonitis and to develop a warning score system, based on easily recognizable and assessable variables, globally accepted.

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In the last three decades, infection (CDI) has increased in incidence and severity in many countries worldwide. The increase in CDI incidence has been particularly apparent among surgical patients. Therefore, prevention of CDI and optimization of management in the surgical patient are paramount.

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Skin and soft-tissue infections (SSTIs) encompass a variety of pathological conditions that involve the skin and underlying subcutaneous tissue, fascia, or muscle, ranging from simple superficial infections to severe necrotizing infections. SSTIs are a frequent clinical problem in surgical departments. In order to clarify key issues in the management of SSTIs, a task force of experts met in Bertinoro, Italy, on June 28, 2018, for a specialist multidisciplinary consensus conference under the auspices of the World Society of Emergency Surgery (WSES) and the Surgical Infection Society Europe (SIS-E).

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Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis.

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Article Synopsis
  • The Global Alliance for Infections in Surgery acknowledges the significant work done by the task force on the Sepsis-3 definitions, viewing it as a major advancement in understanding sepsis.
  • Despite this positive outlook, they have lingering concerns about how the Sepsis-3 definitions are being applied in practice.
  • These concerns have emerged more than a year after the definitions were published, indicating ongoing issues that need to be addressed.
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Background: Purulent pericarditis is an uncommon entity, which is, in very rare cases, associated to infection of the aorta.

Case Presentation: We present the case of a 42-year-old male patient, who was admitted to hospital complaining of tiredness, diarrhea and leg edema. Clinical examination revealed a hypotensive and obviously shocked patient.

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Emergency repair of complicated abdominal wall hernias may be associated with worsen outcome and a significant rate of postoperative complications. There is no consensus on management of complicated abdominal hernias. The main matter of debate is about the use of mesh in case of intestinal resection and the type of mesh to be used.

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Article Synopsis
  • The hs-TnT assay is effective in helping doctors make decisions for low-risk patients with chest pain, though its reliability in this specific group has not been thoroughly documented.
  • In a study involving 48 patients, the hs-TnT levels were measured at three different times to evaluate their ability to predict myocardial ischaemia detected by PET-CT.
  • Results showed a strong negative predictive value (94% at T0, 100% at T2, and 100% at T6), indicating that low hs-TnT levels (<4 ng/L) can confidently rule out significant ischaemia, despite lower accuracy in identifying positive cases.
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Aims: The present study aimed to document a local pattern of care in consecutive patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction (STEMI) in a tertiary centre in Switzerland.

Methods: A retrospective study was conducted at the University Hospital of Lausanne, Switzerland. A total of 389 consecutive patients undergoing primary percutaneous coronary intervention for STEMI between 2009 and 2010 were studied.

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Aim: To investigate the role of laparoscopy in diagnosis and treatment of intra abdominal infections.

Methods: A systematic review of the literature was performed including studies where intra abdominal infections were treated laparoscopically.

Results: Early laparoscopic approaches have become the standard surgical technique for treating acute cholecystitis.

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In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide. The incidence of CDI has also increased in surgical patients. Optimization of management of C difficile, has therefore become increasingly urgent.

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Purpose: The discovery of Imatinib mesylate (Gleevec®) has revolutionized the treatment of GIST, increasing diseasefree survival (DFS) after complete surgical resection of a primary localized GIST and extending overall survival in metastatic disease. The definition of an accurate prognostic system is critical for the therapeutic decision making process. In literature, there are three main prognostic criteria F/NIH consensus, AFIP standards and modified NIH standards.

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Computed tomography (CT) imaging is the most appropriate diagnostic tool to confirm suspected left colonic diverticulitis. However, the utility of CT imaging goes beyond accurate diagnosis of diverticulitis; the grade of severity on CT imaging may drive treatment planning of patients presenting with acute diverticulitis. The appropriate management of left colon acute diverticulitis remains still debated because of the vast spectrum of clinical presentations and different approaches to treatment proposed.

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Background: In recent years, there has been a worldwide increase in infections caused by microorganisms resistant to multiple antimicrobial agents.

Methods: In the past few decades, an increased prevalence of infections caused by antibiotic-resistant pathogens, including Enterococcus spp., carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii, extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella spp.

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Aim: We want to show a new organisational model of General Surgery training, in act in Università Politecnica delle Marche, which sees its strength in the territorial formative network.

Material Of Study: In our Athenaeum, this organization is not a recent realization, but the firsts to have benefited completely of this system are the four residents who have completed the General Surgery formation in March 2014, for this reason we report their experience.

Results: The four residents benefited of the two years in the peripheral structures, two also performed a period in a foreign country, two chose to spend other 6 months in the peripheral structure to prepare the thesis of specialization; surgical activity has been, for each resident, of 400 interventions on average as first operator (237-476) distributed in great surgery 44 (13-80), middle 172 (129-268) and small 209 (70-378).

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Skin and soft tissue infections (SSTIs) encompass a variety of pathological conditions ranging from simple superficial infections to severe necrotizing soft tissue infections. Necrotizing soft tissue infections (NSTIs) are potentially life-threatening infections of any layer of the soft tissue compartment associated with widespread necrosis and systemic toxicity. Successful management of NSTIs involves prompt recognition, timely surgical debridement or drainage, resuscitation and appropriate antibiotic therapy.

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