An exploration of the gut and environmental resistome in a community in northern Vietnam in relation to antibiotic use.

Background: Antibiotic resistance is a major global public health threat. Antibiotic use can directly impact the antibiotic resistant genes (ARGs) profile of the human intestinal microbiome and consequently the environment through shedding.

Methods: We determined the resistome of human feces, animal stools, human food and environmental (rain, well, and irrigative water) samples ( = 304) in 40 households within a community cohort and related the data to antibiotic consumption.