Publications by authors named "Tracy Wing Yee Yeung"
Purpose: To evaluate the effect of 12-month DHEA supplementation on menstrual pattern and ovarian reserve markers in women with premature ovarian insufficiency (POI) METHODS: This is a prospective observational study. Women with POI were given DHEA supplements (25 mg three times daily) for 12 months. Sonographic assessment for ovarian volume and antral follicle count (AFC) and serum measurement for anti-Mullerian hormone (AMH), follicle stimulating hormone (FSH), estradiol, testosterone, liver function, and hemoglobin level were performed at baseline and monthly for 13 months after the supplementation.
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- This study aimed to assess how serum adiponectin levels relate to metabolic syndrome in Chinese women diagnosed with polycystic ovary syndrome (PCOS).
- Researchers conducted a cross-sectional analysis of 116 women at a hospital in Hong Kong between 2010 and 2011, using various clinical and biochemical parameters.
- The results indicated that serum adiponectin, along with age and BMI, is independently linked to metabolic syndrome, suggesting further research is needed to explore its long-term health implications.
Objective: To determine the live birth and cumulative live birth rates of expected poor ovarian responders according to the Bologna criteria and to compare their outcomes with those of expected normal responders.
Design: Retrospective analysis.
Setting: University infertility clinic.
Study Question: Does endometrial injury in the cycle preceding ovarian stimulation for in vitro fertilization (IVF) improve the ongoing pregnancy rate in unselected subfertile women?
Summary Answer: Endometrial injury induced by endometrial aspiration in the preceding cycle does not improve the ongoing pregnancy rate in unselected subfertile women undergoing IVF.
What Is Known Already: Implantation failure remains one of the major limiting factors for IVF success. Mechanical endometrial injury in the cycle preceding ovarian stimulation of IVF treatment has been shown to improve implantation and pregnancy rates in women with repeated implantation failures.
Article Synopsis
- The study aimed to assess whether DHEA supplementation before IVF could enhance ovarian response and IVF outcomes in women expected to have a poor ovarian response.
- The research involved 32 women divided into two groups: one receiving DHEA and the other receiving a placebo, with a focus on measuring various ovarian response markers.
- Results showed that while DHEA supplementation increased certain hormone levels, it did not significantly improve ovarian response indicators or IVF success rates compared to the placebo group.
Objective: To assess the incidence of P elevation (PE) in natural cycles and evaluate its effect on frozen-thawed embryo transfer cycles performed in natural cycles (FET-NC).
Study Design: Retrospective analysis.
Setting: A tertiary assisted reproductive unit.
Article Synopsis
- Preliminary reports indicate that DHEA may be beneficial for women with poor ovarian reserve and primary ovarian insufficiency (POI), but more rigorous studies are needed.
- The study aimed to evaluate the impact of 16 weeks of DHEA treatment on ovarian response markers in 22 women with unexplained POI, compared to a placebo.
- Results showed improved antral follicle counts and ovarian volume in the DHEA group, although serum AMH and FSH levels did not change significantly; higher testosterone and estradiol levels were also noted.
Article Synopsis
- Previous research indicated that combining letrozole with misoprostol improved abortion rates compared to misoprostol alone and linked higher estradiol levels to increased failure rates.
- This pilot study involved 20 participants who received letrozole for 7 days before taking misoprostol, aiming to boost estradiol suppression and complete abortion rates for pregnancies up to 63 days.
- Results showed a 95% complete abortion rate, with most participants (88%) favoring the option of medical termination in the future, indicating that this new method is as effective as the standard regimen.