Publications by authors named "Tracy Jonelis"
Importance: Despite favorable national trends in the incidence of end-stage renal disease (ESRD) from 2008 to 2011, ESRD incidence has been increasing recently, and less than 10% of patients with ESRD start renal replacement therapy with peritoneal dialysis (PD) in the United States. Given known and potential advantages of PD over hemodialysis, the Kaiser Permanente Northern California integrated health care delivery system implemented a program to expand use of PD.
Objectives: To describe the system-level approach to expansion of PD use and temporal trends in initiation and persistence of PD and its associated mortality.
Article Synopsis
- IgM-secreting myelomas and lymphomas, such as Waldenström macroglobulinemia, can lead to various kidney issues, including specific types of glomerulonephritis and amyloid deposits.
- The report discusses five unique cases of kidney pathology observed in patients, featuring intracapillary IgM pseudothrombi and changes associated with microangiopathy, alongside intracellular crystals found in two biopsies.
- Two of the patients exhibited low complement levels when they first presented, contributing to the growing body of research on kidney problems tied to paraprotein-related thrombotic microangiopathy.
Objective: To compare renal function decline, incident end-stage renal disease (ESRD), and mortality among patients with 5 common glomerular diseases in a large diverse population.
Patients And Methods: A retrospective cohort study (between January 1, 2000, and December 31, 2011) of patients with glomerulonephropathy using the electronic health record of an integrated health system was performed. Estimated glomerular filtration rate (eGFR) change, incident ESRD, and mortality were compared among patients with biopsy-proven focal segmental glomerulosclerosis (FSGS), membranous glomerulonephritis (MN), minimal change disease (MCD), immunoglobulin A nephropathy (IgAN), and lupus nephritis (LN).