Psychedelic drugs, known for their perception-altering properties, are gaining popularity in the treatment of mental health and pain disorders. As exploratory studies demonstrate clinical efficacy with few adverse events, it is expected that more patients will ingest psychedelic drugs. For therapeutic reasons, as with any drug, anaesthesiologists must be aware of its physiological effects and contraindications to ensure the safe provision of anaesthesia.
View Article and Find Full Text PDFBackground: Transfusion of red blood cells (RBC) is a common procedure, which when prescribed inappropriately can result in adverse patient outcomes. This study sought to determine the impact of a multi-faceted intervention on unnecessary RBC transfusions at hospitals with a baseline appropriateness below 90%.
Study Design And Methods: A prospective medical chart audit of RBC transfusions was conducted across 15 hospitals.
Background: In this prospective, randomized, observer-blinded study, we compared double-injection (DI) ultrasound-guided supraclavicular block to a novel targeted intracluster-injection (TII) technique, whereby local anesthetic is injected inside the main and satellite neural clusters (confluences of trunks and divisions of the brachial plexus).
Methods: Ninety patients were randomly allocated to receive a DI (n = 45) or TII (n = 45) technique for ultrasound-guided supraclavicular block. The local anesthetic drug (lidocaine 1.
Background And Objectives: The aim of this study was to determine the minimum effective volume (MEV) of combined lidocaine 1.0%-bupivacaine 0.25% with epinephrine 5 μg/mL in 90% of patients (MEV90) for ultrasound-guided subparaneural popliteal sciatic nerve block.
View Article and Find Full Text PDFBackground: Knee pain is one of the major sources of pain and disability in developed countries, particularly in aging populations, and is the primary indication for total knee arthroplasty (TKA) in patients with osteoarthritis (OA).
Objectives: To determine the presence of myofascial pain in OA patients waitlisted for TKA and to determine whether their knee pain may be alleviated by trigger point injections.
Methods: Following ethics approval, 25 participants were recruited from the wait list for elective unilateral primary TKA at the study centre.