Publications by authors named "Tracy A Gieringer"
Article Synopsis
- A study confirmed that a specific region on mouse Chromosome 1 is linked to seizure susceptibility differences between seizure-resistant C57BL/6 and seizure-sensitive DBA/2 mice, narrowing down the area to a 4.1-Mb critical interval.
- Within this interval, researchers identified 12 genes with variations (SNPs) that could affect protein function, focusing particularly on the Kcnj10 gene as a significant factor influencing seizure susceptibility.
- The findings suggest that the B6 variant of Kcnj10 is associated with higher seizure thresholds, indicating its potential role in understanding seizure genetics and physiology in mice.
