Phone-based telemonitoring of arterial hypertension versus usual care: the HOROSCOPE study.

The Horoscope trial aimed to assess the efficacy of home blood pressure (BP) telemonitoring (TLM) in controlling BP reduction in hypertensive patients compared with usual care. This is a multi-center, prospective randomized, parallel-group trial comparing TLM with usual care during a period of 6 months in patients with hypertension. We included 525 patients randomly assigned in a 1-1 ratio to telemonitoring (TLM group; n = 260) or usual care (control group; n = 265).

Extraction, Purification, Characterization, and Wound Healing Effects of Novel Prickly Pear ( (L.) Mill.) Heteropolysaccharides.

The present study undertakes the purification of a novel polysaccharide from Tunisian prickly pear (L.) Mill.) rackets (PPPRs) and the determination of its physicochemical properties, structure, antibacterial and antioxidant properties, as well as its in vitro and in vivo wound healing potential.

Canine olfactory detection and its relevance for the medical identification of patients with COVID-19.

Introduction: The assessment of Volatile Organic Compounds (VOCs) in exhaled breath or sweat represents a potential non-invasive and rapid diagnostic tool for respiratory diseases.

Objective: To determine if trained dogs can reliably identify the odour associated with COVID19.

Methods: This is a monocentric prospective study carried out in the Emergency Department (ED) of a university hospital fromJulyto November 2021.

Melatonin, vitamins and minerals supplements for the treatment of Covid-19 and Covid-like illness: A prospective, randomized, double-blind multicenter study.

Background: Melatonin, zinc, and multivitamins are among most recommended supplements in the fight against coronavirus disease 2019 (COVID-19). We aimed to examine the efficacy and safety of this association in the treatment of COVID-19 and COVID-like illnesses.

Methods: We conducted a multicenter prospective, randomized, double-blind, controlled trial.

Effects of a Novel Lin Seed Polysaccharide on Beef Sausage Properties.

Functional ingredients are substances that offer health benefits beyond their nutritional value. A novel heteropolysaccharide, named water soluble polysaccharide (LWSP) was purified from L. seeds powder and identified, via TLC and NMR, as a polymer composite of α1-2-L-arabinose, β1-2-D-xylose, β1-2-D-mannose and α1-2-D-glucose.

Twice-Daily Oral Zinc in the Treatment of Patients With Coronavirus Disease 2019: A Randomized Double-Blind Controlled Trial.

Background: Zinc supplementation has been considered a potential therapy for coronavirus disease 2019 (COVID-19). We aimed to examine zinc efficacy in adult patients with COVID-19 infection.

Methods: We conducted a prospective, randomized, double-blind, placebo-controlled multicenter trial.

Analgesic Effect of Topical Piroxicam vs Phytotherapy Gel in the Treatment of Acute Soft Tissue Injuries: A Randomized Controlled Noninferiority Study.

Objective: The study compared the efficacy and tolerability of piroxicam gel and a new topical combination of medicinal plant products (Soulagel®; Belpharma Tunisia) to treat pain caused by soft tissue injuries.

Methods: Patients (n = 1,525) were assigned to receive piroxicam gel or Soulagel. Efficacy assessments included a change of at least 50% in the pain-on-movement visual numeric scale rating from emergency department discharge (baseline) to day 7 final assessment, as well as the time required to reach pain resolution criteria, the need for rescue analgesia, patients' satisfaction, and the rate of adverse effects.

Extraction, Characterization, and Structure of a Novel Heteropolysaccharide from Lepidium sativum and Its Effects on Wound Healing in Diabetic Rats.

The present study undertakes the extraction of a novel polysaccharide from Lepidium sativum (PLS) and the determination of its physicochemical composition and antioxidant properties, as well as its potential wound healing activity in alloxan-induced diabetic rats. This polysaccharide presented a lighter natural color, whose luminosity (∗), red-green intensity (∗), and blue-yellow intensity (∗) were recorded at 63.26, 5.

Bio-preservation Effect of Probiotic Lactiplantibacillus plantarum S61 Against Rhodotorula glutinis and Listeria monocytogenes in Poultry Meat.

The objective of this work is the study of the antifungal and antibacterial activity of Lactiplantibacillus plantarum S61 strains, isolated from traditional fermenting green olives against Rhodotorula glutinis UMP 22 and Listeria monocytogenes ATCC 19117, and its application in meat as bio-preservative agent. The cell-free supernatant (CFS) of Lpb. plantarum S61 shows high inhibition zones, which are 22.

Two-day seven-day course of levofloxacin in acute COPD exacerbation: a randomized controlled trial.

Introduction: Duration of antibiotic treatment in acute exacerbation of COPD (AECOPD) is most commonly based on expert opinion. Typical administration periods range from 5 to 7 days. A 2-day course with levofloxacin was not previously assessed.

Antioxidant activities, functional properties, and application of a novel polysaccharide in the formulation of cake.

A novel heteropolysaccharide, named cress water soluble polysaccharide (CWSP), was purified from seeds. Antioxidant activities and functional properties were characterized thermally using thermal gravimetric analysis (TGA), and the differential scanning calorimeter (DSC) results of CWSP were evaluated. The total antioxidant capacity and the metal chelating activities of CWSP at 3 mg/ml were equivalent to 116.

A novel probiotic strain, Lactiplantibacillus plantarum LC38, isolated from Tunisian camel milk promoting wound healing in Wistar diabetic rats.

Antimicrobial and probiotic properties were sought in Tunisian raw camel milk. One hundred and forty strains were isolated for this purpose. Initially, a screening based on growth kinetics under gastrointestinal tract (GIT) conditions allowed us to select only one strain that showed good resistance to pH 3 and 5% bovine bile.

Value of Dynamic Variation of Impedance Cardiac output in the diagnosis of Heart Failure in emergency department patients with undifferentiated dyspnea.

Aim Of Study: Cardiac output (CO) responses to acute changes in body position and Valsalva maneuver (VM) were proposed to assess cardiac contractile reserve. We investigated the value of sitting position (SP), leg raising (LR), and VM for identifying heart failure (HF) in patients with undifferentiated dyspnea.

Materials And Methods: It is a prospective study including patients over 18 years old admitted to the emergency department (ED) for dyspnea.

Chlorophyll content and fluorescence as physiological parameters for monitoring Orobanche foetida Poir. infection in faba bean.

Orobanche spp. are root parasitic plants that cause yield losses in faba bean (Vicia faba L.).

2-Day versus C-reactive protein guided antibiotherapy with levofloxacin in acute COPD exacerbation: A randomized controlled trial.

Introduction: Duration of antibiotic treatment in acute exacerbation of COPD (AECOPD) is most commonly based on expert opinion. Biomarker guided strategy is increasingly recommended to limit unnecessary antibiotic use. We performed a randomized controlled study to evaluate the efficacy of 2-day versus C-reactive protein (CRP)-guided treatment with levofloxacin in patients with AECOPD.

Structure Analysis and Antioxidant Activity of a Novel Polysaccharide from Katan Seeds.

In the present work, a novel water-soluble polysaccharide (LWSP) was purified from Katan seeds. Polysaccharide was structurally characterized by NMR spectroscopic analysis, thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), Fourier-transform infrared spectroscopy (FTIR) analysis, X-ray diffraction (XRD), and UV absorption. TLC and HPLC showed that LWSP was a polysaccharide consisted mainly of glucose, mannose, xylose, and arabinose.

Value of systolic time intervals in the diagnosis of heart failure in emergency department patients with undifferentiated dyspnea.

Aim Of The Study: The diagnosis of heart failure in the emergency department (ED) is challenging. The aim of this study was to evaluate systolic time intervals (STIs) using phonoelectrocardiography for the diagnosis of heart failure (HF) in ED patients with undifferentiated dyspnea.

Methods: A total of 855 patients with dyspnea and suspected HF were prospectively enrolled.