[Effect of cpap therapy on sleep quality in patients with OSAS].

Unlabelled: For an adequate analysis of sleep quality was assessed a new composed index wich objectively approached variate polisomnographic parameters. We used this new concept--sleep disturbances index-SDI in patients with obstructive sleep apnea (OSAS), before and after the beginning of CPAP therapy.

Material And Method: 41 patients were evaluated and for each one we calculated SDI score.

[Expression of Ki-67 in bronchial asthma].

Unlabelled: In this paper we want to study the changes in the expression of cell proliferation factor Ki67 in the respiratory epithelium of patients diagnosed with bronchial asthma.

Material And Methods: Twenty one patients with bronchial asthma having different degrees of severity (according to GINA 2002) have been included in our study. Fragments of bronchial mucosa were obtained through fiberbronchoscopy, prepared for histologic examination in view of immune marking with anti-Ki67 antibodies.

Adipokines involvement in lung function.

The last two decades brings many data about white adipose tissue capacity to secrete hormones, named adipokines, which could mediate the relationship between obesity and lung diseases. In this paper we presented some data about adipokines involvement on pulmonary function, with special emphasis on leptin, adiponectin, tumor necrosis factor alpha, vascular endothelial growth factor, resistin, hepatocyte growth factor, interleukin-6, angiotensinogen and apelin.

[Difficulties in the treatment of pulmonary tuberculosis in children].

Unlabelled: The management of pulmonary tuberculosis in children in Romania is done according to ERS, WHO and IUATLD recommendations, Iaşi area being included since 1998 in the pilot study.

Material And Method: We analyzed in a descriptive and retrospective study 254 children with pulmonary tuberculosis admitted to the Iaşi Department of Pediatric Lung Diseases in the interval January 2000 - December 2005. The surveyed parameters included: treatment course, side effects of antituberculous drugs, and an assessment of the cases at the end of treatment.

Th1 and Th2 cytokine response in patients with pulmonary tuberculosis and health care workers occupationally exposed to M. tuberculosis.

Unlabelled: Aiming to detect reliable markers indicating protection from or susceptibility to tuberculosis infection, we investigated both Th1/Th2 cytokines and total IgE plasma levels in health care workers occupationally exposed to M. tuberculosis, in patients with pulmonary tuberculosis and in healthy persons.

Material And Method: The study groups have included 15 health care workers in close contact with TB patients, patients with active pulmonary tuberculosis at diagnosis and after treatment (12 advanced and 10 moderate TB, of which 6 had also pleurisy) and 20 healthy volunteers.

[Pulmonary fibrosis induced by amiodarone--a pitfall of antiarrhytmic treatment].

Cardiac arrhythmia are one of the major causes of cardiovascular and general morbi-mortality. This is the reason for a very quick and well-guided approach. One of the most used drug for this purpose is amiodarone, due to its high therapeutic potency and despite its risk for adverse effects.

[Diagnostic difficulties in pulmonary tuberculosis in children].

Unlabelled: Pulmonary tuberculosis in children remains an important cause of morbidity and mortality around the world.

Aim: To evaluate the difficulty of diagnosis and the epidemiological, clinical, radiological and bacteriological features of pulmonary tuberculosis in children.

Material And Method: We analyzed in a descriptive and retrospective study, 254 children with pulmonary tuberculosis hospitalized in Pulmonary Pediatric Department of Iaşi during Jan 2000 - Dec 2005.

[Nocturnal asthma].

Nocturnal asthma is one of the difficult form of asthma. It is associated with significant decline in pulmonary function and increase of airway inflammation at night. The pathophysiological mechanisms underlying the nocturnal aggravation of asthma are intricate.

[Thoracoscopic pleurodesis in malignant pleural effusions].

We performed retrospectively study on 136 thoracoscopies done in our clinic in the period January 2000 and December 2004. We reviewed 136 thoracoscopies, 71 patients were male and 65 were female (mean age 58.4 years).

[Assessing the number of TB cases using the capture-recapture method with two data sources].

Aim: A more accurate assessment of the number of TB cases in Iaşi County using the capture-recapture method.

Methods: TB patients diagnosed in Iaşi County are included in the Registry of Tuberculosis, and are microbiologically examined. The Registry of Tuberculosis in Iaşi County contains data about the diagnosis and treatment of TB patients that live in this area (notification).

[Treatment of pulmonary hypertension in COPD: is there hope for the better?].

The aim of this study is to prove for a well tolerated medication (clinical and financial) a supplementary effect in improvement prognosis of patients with pulmonary hypertension secondary to COPD, already treated with classical pneumology drugs. Three pts. groups were selected: the first received only classical pneumology treatment, the second with supplementary therapy by IECA and Ca-blockers, the third with supplementary therapy with IECA and nebivolol; the follow-up protocol included clinical and paraclinical status (blood gases, spirometry, ECG, echocardiography, 6 minute walk test) over 3 months.