Publications by authors named "Toyoaki Kobayashi"

Background: Facial massage is empirically known to be associated with morphological changes, such as improvements in facial sagging. However, quantified objective evaluations of massage-induced changes have not been performed to date. This preliminary pilot study aimed to verify the effectiveness of facial massages by using breakthrough computed tomographic technology.

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Article Synopsis
  • Desmosine and isodesmosine are important crosslinking amino acids in elastin, which is crucial for the structure of skin.
  • Previous attempts to measure these crosslinkers in human skin have struggled due to the insoluble nature of elastin proteins.
  • This study successfully synthesized isotopically labeled desmosine and used advanced analysis techniques to quantitatively measure desmosine levels in human skin for the first time, detecting approximately 1.43 μg from 1 mg of dry skin.
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Autotransplantation can be a viable alternative to dental implant placement for partially edentulous patients when case selection and surgical procedures are performed properly. Moreover, in the event of a failed autotransplantation, implant placement may still be possible. Autotransplantation offers several benefits compared with dental implants, however the surgical procedure is technique sensitive.

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Aims: This review assessed the available evidence on the performance of CAD/CAM monolithic implant-supported restorations bonded to titanium (Ti) inserts and bases, which has become a popular concept.

Materials And Methods: An electronic and manual search of PubMed databases was conducted to identify studies published in English between 2000 and 2016 on the performance of monolithic ceramic implant restorations with Ti inserts.

Results: The initial search revealed 505 titles.

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Determination of the appropriate conditions for protein crystallization remains a highly empirical process. Preventing protein aggregation is necessary for the formation of single crystals under aggregation-prone solution conditions. Because many amino acids and amino acid derivatives offer a unique combination of solubility and stabilizing properties, they open new avenues into the field of protein aggregation research.

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