Insecticide-treated nets provide protection against malaria to children in an area of insecticide resistance in Southern Benin.

Background: Malaria control is heavily reliant on insecticides, especially pyrethroids. Resistance of mosquitoes to insecticides may threaten the effectiveness of insecticide-based vector control and lead to a resurgence of malaria in Africa.

Methods: In 21 villages in Southern Benin with high levels of insecticide resistance, the resistance status of local vectors was measured at the same time as the prevalence of malaria infection in resident children.

Therapeutic efficacy of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Benin.

Background: Artemether/lumefantrine (Coartem(®)) has been used as a treatment for uncomplicated Plasmodium falciparum infection since 2004 in Benin. This open-label, non-randomized study evaluated efficacy of artemether-lumefantrine (AL) in treatment of uncomplicated falciparum malaria in children aged 6-59 months in two malaria transmission sites in northwest Benin.

Methods: A 42-day therapeutic efficacy study was conducted between August and November 2014, in accordance with 2009 WHO guidelines.

[Epidemiology of urinary schistosomiasis among school children in Péhunco area, Northern Benin. Malacological survey].

Schistosomiasis is a public health problem in Benin but prevalence estimates vary widely. Parasitological (from May to September 2010) and malacological surveys (from September 2010 to June 2012) were conducted to determine the current status of urinary schistosomiasis among 1 585 schoolchildren from 18 primary schools of Péhunco area, North-West Benin, using two parasitological tests. Pupils were enrolled with a mean age of 11 years (from 7 to 16 years-old age) and 51.

High rates of parasite recrudescence following intermittent preventive treatment with sulphadoxine-pyrimethamine during pregnancy in Benin.

Background: Despite widespread parasite resistance to sulphadoxine-pyrimethamine (SP) its use for intermittent preventative treatment during pregnancy remains the policy in Benin and throughout most of sub-Saharan Africa.

Methods: In a prospective study, 982 pregnant women were recruited in Benin and followed until delivery. The prevalence of point mutations in the pfdhfr and pfdhps genes associated with Plasmodium falciparum resistance to SP during consecutive antenatal visits was determined.