The First Report of a Methicillin-Resistant Isolate Harboring Type IV SCC in Thailand.

Methicillin-resistant (MRSA) is mostly found in Thailand in the hospital as a nosocomial pathogen. This study aimed to report the genetic characterization of a clinical community-acquired MRSA (CA-MRSA) isolate collected from hospitalized patients in Thailand. Among 26 MRSA isolates, no.

Antimicrobial Susceptibility among Colistin, Sulbactam, and Fosfomycin and a Synergism Study of Colistin in Combination with Sulbactam or Fosfomycin against Clinical Isolates of Carbapenem-Resistant .

This study aimed to determine the activity of colistin plus sulbactam and colistin plus fosfomycin against carbapenem-resistant (CRAB). Fifteen clinical isolates were obtained from patients admitted to Phyathai II International Hospital, Bangkok, Thailand, from August 2014 to April 2015. The antimicrobial susceptibilities of colistin, sulbactam, and fosfomycin were evaluated using the E-test or broth microdilution and the synergistic activity of the antibacterial combinations (colistin plus sulbactam or fosfomycin) was determined using the chequerboard method.

EMERGENCE OF CO-CARBAPENEMASE GENES, BLA(OXA23), BLA(VIM) AND BLA(NDM) IN CARBAPENEMRESISTANT ACINETOBACTER BAUMANNII CLINICAL ISOLATES.

This study investigated presence of carbapenemase genes among carbapenem-resistant Acinetobacter baumannii (CRAB) clinical isolates and their clonal relationships. Fifty-six CRAB isolates were collected from patients admitted to Hua Hin Hospital, Prachuap Khiri Khan, Thailand. PCR amplification and DNA sequencing were used to identify blaOXA23, blaOXA40, blaOXA58, blaVIM, blaSIM and blaNDM.

Plasmid metagenomics reveals multiple antibiotic resistance gene classes among the gut microbiomes of hospitalised patients.

Antibiotic resistance genes are rapidly spread between pathogens and the normal flora, with plasmids playing an important role in their circulation. This study aimed to investigate antibiotic resistance plasmids in the gut microbiome of hospitalised patients. Stool samples were collected from seven inpatients at Siriraj Hospital (Bangkok, Thailand) and were compared with a sample from a healthy volunteer.

DETECTION OF NEW DELHI METALLO-BETA-LACTAMASE-1-PRODUCING KLEBSIELLA PNEUMONIAE AT A GENERAL HOSPITAL IN THAILAND.

The purpose of this study was to detect carbapenemase genes in clinical isolates of carbapenem-resistant Enterobacteriaceae (CRE) obtained from patients admitted to Hua-Hin Hospital, Prachuab Khiri Khan Province, Thailand between January and December 2014. Screening of CRE was initially determined using disk diffusion method, and subsequently using modified Hodge test (MHT). Multiplex PCR was employed to amplify carbapenemase genes, blaIMP, blaOXA-48, blaNDM blaKPC, and blaVIM.

Identification and characterization of carbapenemase genes in clinical isolates of carbapenem-resistant Acinetobacter Baumannii from general hospital in Thailand.

This study identified, using PCR blaoxA,,23 encoding carbapenamase OXA-23 in 42 carbapenem-resistant Acinetobacter baumannii (CRAB) clinical iso- lates and blaOXA-40-like encoding carbapenamase OXA-40-like in one isolate (the first such Thai sample) obtained from patients admitted to Hua Hin Hospital, Thailand during November 2011-September 2012. Using repetitive extragenic palindromic PCR, the isolates could be divided into 4 different clones, with 40 isolates belonging to clone A and the remaining to B, C and D. Other resistance in CRAB needs to be investigated.