Publications by authors named "Toshiyuki Saeki"
Article Synopsis
- Researchers discovered that a polyphenol from brown algae can inhibit the differentiation of fibroblasts into fat cells, known as adipocytes.
- In an experiment, this compound was given to mice on a high-fat diet, which resulted in reduced fat accumulation, similar to that of mice on a normal diet.
- The study concluded that the Pin1 protein is essential for the conversion of stem cells into adipocytes and suggested that the brown algae polyphenol may offer a potential treatment for obesity.
Establishment of adipose-derived mesenchymal stem cell lines from a p53-knockout mouse.
Biochem Biophys Res Commun
October 2012
Mesenchymal stem cells (MSCs) can differentiate into a variety of cell types. MSCs exist in several tissues such as the bone marrow, adipose, muscle, cartilage, and tendon. This differentiation potential makes MSCs candidates for cell-based therapeutic strategies for mesenchymal tissue injuries.
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